Management of Diabetic Ketoacidosis in Pregnancy

Nicholas R. Spencer, Shannon M. Clark, Hassan M. Harirah

Research output: Contribution to journalArticlepeer-review


Diabetic ketoacidosis (DKA) is a rare, but potentially life-threatening complication of diabetes. Certain physiological changes during pregnancy predispose pregnant individuals to developing DKA. Early recognition and aggressive treatment are essential to avoid maternal and fetal morbidity and mortality. Although laboratory values can help to support, pregnant patients with DKA may not meet the usual criteria and the diagnosis can be made clinically. The key components to treatment include volume replacement, insulin infusion, correction of serum potassium, and fetal monitoring. With appropriate treatment, maternal mortality is low. After recovery, steps should be taken to avoid recurrence.

Original languageEnglish (US)
Pages (from-to)186-195
Number of pages10
JournalClinical Obstetrics and Gynecology
Issue number1
StatePublished - Mar 1 2023
Externally publishedYes


  • critical care
  • diabetes
  • diabetic ketoacidosis
  • obstetrics
  • pregnancy

ASJC Scopus subject areas

  • Obstetrics and Gynecology


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