Management of node-positive melanoma in the era of sentinel node biopsy

Rebekah R. White; Douglas S. Tyler

doi:10.1016/S0960-7404(00)00042-6

Management of node-positive melanoma in the era of sentinel node biopsy

Rebekah R. White, Douglas S. Tyler

Research output: Contribution to journal › Article › peer-review

9 Scopus citations

Abstract

Regional lymph node metastasis is a powerful predictor of decreased overall survival from malignant melanoma. However, the therapeutic value of elective node dissections and the role of adjuvant therapy for node-positive disease have been highly controversial. Sentinel lymph node biopsy has reshaped the debate by allowing for staging of the regional lymph nodes with less morbidity and greater accuracy. This review summarizes the current consensus on the management of node-positive melanoma in the era of sentinel lymph node biopsy.

Original language	English (US)
Pages (from-to)	119-125
Number of pages	7
Journal	Surgical oncology
Volume	9
Issue number	3
DOIs	https://doi.org/10.1016/S0960-7404(00)00042-6
State	Published - Nov 2000
Externally published	Yes

Keywords

Adjuvant therapy
Lymph node dissection
Lymph node metastasis
Melanoma
Sentinel lymph node biopsy

ASJC Scopus subject areas

Surgery
Oncology

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10.1016/S0960-7404(00)00042-6

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abstract = "Regional lymph node metastasis is a powerful predictor of decreased overall survival from malignant melanoma. However, the therapeutic value of elective node dissections and the role of adjuvant therapy for node-positive disease have been highly controversial. Sentinel lymph node biopsy has reshaped the debate by allowing for staging of the regional lymph nodes with less morbidity and greater accuracy. This review summarizes the current consensus on the management of node-positive melanoma in the era of sentinel lymph node biopsy.",

keywords = "Adjuvant therapy, Lymph node dissection, Lymph node metastasis, Melanoma, Sentinel lymph node biopsy",

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AU - White, Rebekah R.

AU - Tyler, Douglas S.

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N2 - Regional lymph node metastasis is a powerful predictor of decreased overall survival from malignant melanoma. However, the therapeutic value of elective node dissections and the role of adjuvant therapy for node-positive disease have been highly controversial. Sentinel lymph node biopsy has reshaped the debate by allowing for staging of the regional lymph nodes with less morbidity and greater accuracy. This review summarizes the current consensus on the management of node-positive melanoma in the era of sentinel lymph node biopsy.

AB - Regional lymph node metastasis is a powerful predictor of decreased overall survival from malignant melanoma. However, the therapeutic value of elective node dissections and the role of adjuvant therapy for node-positive disease have been highly controversial. Sentinel lymph node biopsy has reshaped the debate by allowing for staging of the regional lymph nodes with less morbidity and greater accuracy. This review summarizes the current consensus on the management of node-positive melanoma in the era of sentinel lymph node biopsy.

KW - Adjuvant therapy

KW - Lymph node dissection

KW - Lymph node metastasis

KW - Melanoma

KW - Sentinel lymph node biopsy

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ER -

Management of node-positive melanoma in the era of sentinel node biopsy

Abstract

Keywords

ASJC Scopus subject areas

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