Marine ω-3 fatty acid intake: Associations with cardiometabolic risk and response to weight loss intervention in the Look AHEAD (Action for Health in Diabetes) study

L. Maria Belalcazar; David M. Reboussin; Steven M. Haffner; Rebecca S. Reeves; Dawn C. Schwenke; Ron C. Hoogeveen; F. Xavier Pi-Sunyer; Christie M. Ballantyne

doi:10.2337/dc09-1235

Marine ω-3 fatty acid intake: Associations with cardiometabolic risk and response to weight loss intervention in the Look AHEAD (Action for Health in Diabetes) study

L. Maria Belalcazar
, David M. Reboussin
, Steven M. Haffner
, Rebecca S. Reeves
, Dawn C. Schwenke
, Ron C. Hoogeveen
, F. Xavier Pi-Sunyer
, Christie M. Ballantyne

Internal Medicine

Research output: Contribution to journal › Article › peer-review

26 Scopus citations

Abstract

OBJECTIVE - To examine usual marine ω-3 fatty acid (mO-3FA) intake in individuals with diabetes; its association with adiposity, lipid, and glucose control; and its changes with behavioral lifestyle intervention for weight loss. RESEARCH DESIGN AND METHODS - Cross-sectional and 1-year longitudinal analyses were performed on 2,397 Look AHEAD (Action for Health in Diabetes) participants. Look AHEAD is a cardiovascular outcome trial evaluating the effects of intensive lifestyle intervention for weight loss in overweight/obese subjects with type 2 diabetes. RESULTS - Baseline mO-3FA intake was 162±138 mg/day. It was inversely associated with triglycerides (β = -0.41, P < 0.001) and weakly with HDL (β = 4.14, P = 0.050), after multiple covariate adjustment. One-year mO-3FA and fried/sandwich fish intake decreased with intensive lifestyle intervention (P < 0.001). CONCLUSIONS - mO-3FA intake in Look AHEAD participants was low but associated favorably with lipids. These results encourage investigation on the potential benefits of increasing mO-3FA intake in lifestyle interventions for weight loss in individuals with diabetes.

Original language	English (US)
Pages (from-to)	197-199
Number of pages	3
Journal	Diabetes care
Volume	33
Issue number	1
DOIs	https://doi.org/10.2337/dc09-1235
State	Published - Jan 2010

ASJC Scopus subject areas

Internal Medicine
Endocrinology, Diabetes and Metabolism
Advanced and Specialized Nursing

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Belalcazar, L. M., Reboussin, D. M., Haffner, S. M., Reeves, R. S., Schwenke, D. C., Hoogeveen, R. C., Pi-Sunyer, F. X., & Ballantyne, C. M. (2010). Marine ω-3 fatty acid intake: Associations with cardiometabolic risk and response to weight loss intervention in the Look AHEAD (Action for Health in Diabetes) study. Diabetes care, 33(1), 197-199. https://doi.org/10.2337/dc09-1235

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title = "Marine ω-3 fatty acid intake: Associations with cardiometabolic risk and response to weight loss intervention in the Look AHEAD (Action for Health in Diabetes) study",

abstract = "OBJECTIVE - To examine usual marine ω-3 fatty acid (mO-3FA) intake in individuals with diabetes; its association with adiposity, lipid, and glucose control; and its changes with behavioral lifestyle intervention for weight loss. RESEARCH DESIGN AND METHODS - Cross-sectional and 1-year longitudinal analyses were performed on 2,397 Look AHEAD (Action for Health in Diabetes) participants. Look AHEAD is a cardiovascular outcome trial evaluating the effects of intensive lifestyle intervention for weight loss in overweight/obese subjects with type 2 diabetes. RESULTS - Baseline mO-3FA intake was 162±138 mg/day. It was inversely associated with triglycerides (β = -0.41, P < 0.001) and weakly with HDL (β = 4.14, P = 0.050), after multiple covariate adjustment. One-year mO-3FA and fried/sandwich fish intake decreased with intensive lifestyle intervention (P < 0.001). CONCLUSIONS - mO-3FA intake in Look AHEAD participants was low but associated favorably with lipids. These results encourage investigation on the potential benefits of increasing mO-3FA intake in lifestyle interventions for weight loss in individuals with diabetes.",

author = "Belalcazar, \{L. Maria\} and Reboussin, \{David M.\} and Haffner, \{Steven M.\} and Reeves, \{Rebecca S.\} and Schwenke, \{Dawn C.\} and Hoogeveen, \{Ron C.\} and Pi-Sunyer, \{F. Xavier\} and Ballantyne, \{Christie M.\}",

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doi = "10.2337/dc09-1235",

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AU - Reboussin, David M.

AU - Haffner, Steven M.

AU - Reeves, Rebecca S.

AU - Schwenke, Dawn C.

AU - Hoogeveen, Ron C.

AU - Pi-Sunyer, F. Xavier

AU - Ballantyne, Christie M.

PY - 2010/1

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N2 - OBJECTIVE - To examine usual marine ω-3 fatty acid (mO-3FA) intake in individuals with diabetes; its association with adiposity, lipid, and glucose control; and its changes with behavioral lifestyle intervention for weight loss. RESEARCH DESIGN AND METHODS - Cross-sectional and 1-year longitudinal analyses were performed on 2,397 Look AHEAD (Action for Health in Diabetes) participants. Look AHEAD is a cardiovascular outcome trial evaluating the effects of intensive lifestyle intervention for weight loss in overweight/obese subjects with type 2 diabetes. RESULTS - Baseline mO-3FA intake was 162±138 mg/day. It was inversely associated with triglycerides (β = -0.41, P < 0.001) and weakly with HDL (β = 4.14, P = 0.050), after multiple covariate adjustment. One-year mO-3FA and fried/sandwich fish intake decreased with intensive lifestyle intervention (P < 0.001). CONCLUSIONS - mO-3FA intake in Look AHEAD participants was low but associated favorably with lipids. These results encourage investigation on the potential benefits of increasing mO-3FA intake in lifestyle interventions for weight loss in individuals with diabetes.

AB - OBJECTIVE - To examine usual marine ω-3 fatty acid (mO-3FA) intake in individuals with diabetes; its association with adiposity, lipid, and glucose control; and its changes with behavioral lifestyle intervention for weight loss. RESEARCH DESIGN AND METHODS - Cross-sectional and 1-year longitudinal analyses were performed on 2,397 Look AHEAD (Action for Health in Diabetes) participants. Look AHEAD is a cardiovascular outcome trial evaluating the effects of intensive lifestyle intervention for weight loss in overweight/obese subjects with type 2 diabetes. RESULTS - Baseline mO-3FA intake was 162±138 mg/day. It was inversely associated with triglycerides (β = -0.41, P < 0.001) and weakly with HDL (β = 4.14, P = 0.050), after multiple covariate adjustment. One-year mO-3FA and fried/sandwich fish intake decreased with intensive lifestyle intervention (P < 0.001). CONCLUSIONS - mO-3FA intake in Look AHEAD participants was low but associated favorably with lipids. These results encourage investigation on the potential benefits of increasing mO-3FA intake in lifestyle interventions for weight loss in individuals with diabetes.

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Marine ω-3 fatty acid intake: Associations with cardiometabolic risk and response to weight loss intervention in the Look AHEAD (Action for Health in Diabetes) study

Abstract

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