Abstract
Hybridomas obtained from (NFS x AKR)F1 mice immunized with syngeneic cells infected with AKR-247 MCF virus produced antibodies specific for only AKR-247 or closely related MCF viruses which share a previously defined MCF antigen (MCFA-3). These monoclonal antibodies recognized a new type of viral antigenic determinant which appeared to be a conformational determinant associated with the env precursor polyprotein (pr80(env)) or its disulfide-linked gp70-p15(E) complex (gp80) but not with free gp70 or p15(E) or any other virion or virus-induced protein.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 1112-1117 |
| Number of pages | 6 |
| Journal | Journal of virology |
| Volume | 41 |
| Issue number | 3 |
| DOIs | |
| State | Published - 1982 |
| Externally published | Yes |
ASJC Scopus subject areas
- Microbiology
- Immunology
- Insect Science
- Virology
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