Mechanical Ventilation and Acute Respiratory Distress Syndrome

Victor J. Cardenas, James E. Lynch

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

Acute respiratory distress syndrome continues to be a high-mortality condition. The role of mechanical ventilation remains primarily a supportive modality. Recent research has elucidated the adverse impact of traditional ventilation strategies on development of the disease and, ultimately, mortality. The institution of low tidal volume ventilation has been the only intervention that has resulted in definitive improvement in survival. Animal and human investigations that culminated in the Acute Respiratory Distress Syndrome Network low tidal volume study are reviewed. Current controversies in the application of mechanical ventilation including the use of positive end-expiratory pressure, recruitment maneuvers, and high frequency oscillatory ventilation are also addressed.

Original languageEnglish (US)
Pages (from-to)8-12
Number of pages5
JournalSeminars in Thoracic and Cardiovascular Surgery
Volume18
Issue number1
DOIs
StatePublished - 2006

Fingerprint

Tidal Volume
Adult Respiratory Distress Syndrome
Artificial Respiration
High-Frequency Ventilation
Positive-Pressure Respiration
Mortality
Ventilation
Survival
Research

Keywords

  • ARDS
  • low tidal volumes
  • lung protective strategies
  • mechanical ventilation

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

Mechanical Ventilation and Acute Respiratory Distress Syndrome. / Cardenas, Victor J.; Lynch, James E.

In: Seminars in Thoracic and Cardiovascular Surgery, Vol. 18, No. 1, 2006, p. 8-12.

Research output: Contribution to journalArticle

Cardenas, Victor J. ; Lynch, James E. / Mechanical Ventilation and Acute Respiratory Distress Syndrome. In: Seminars in Thoracic and Cardiovascular Surgery. 2006 ; Vol. 18, No. 1. pp. 8-12.
@article{3c545ea681fd4935b00436df6ba663f3,
title = "Mechanical Ventilation and Acute Respiratory Distress Syndrome",
abstract = "Acute respiratory distress syndrome continues to be a high-mortality condition. The role of mechanical ventilation remains primarily a supportive modality. Recent research has elucidated the adverse impact of traditional ventilation strategies on development of the disease and, ultimately, mortality. The institution of low tidal volume ventilation has been the only intervention that has resulted in definitive improvement in survival. Animal and human investigations that culminated in the Acute Respiratory Distress Syndrome Network low tidal volume study are reviewed. Current controversies in the application of mechanical ventilation including the use of positive end-expiratory pressure, recruitment maneuvers, and high frequency oscillatory ventilation are also addressed.",
keywords = "ARDS, low tidal volumes, lung protective strategies, mechanical ventilation",
author = "Cardenas, {Victor J.} and Lynch, {James E.}",
year = "2006",
doi = "10.1053/j.semtcvs.2006.01.002",
language = "English (US)",
volume = "18",
pages = "8--12",
journal = "Seminars in Thoracic and Cardiovascular Surgery",
issn = "1043-0679",
publisher = "W.B. Saunders Ltd",
number = "1",

}

TY - JOUR

T1 - Mechanical Ventilation and Acute Respiratory Distress Syndrome

AU - Cardenas, Victor J.

AU - Lynch, James E.

PY - 2006

Y1 - 2006

N2 - Acute respiratory distress syndrome continues to be a high-mortality condition. The role of mechanical ventilation remains primarily a supportive modality. Recent research has elucidated the adverse impact of traditional ventilation strategies on development of the disease and, ultimately, mortality. The institution of low tidal volume ventilation has been the only intervention that has resulted in definitive improvement in survival. Animal and human investigations that culminated in the Acute Respiratory Distress Syndrome Network low tidal volume study are reviewed. Current controversies in the application of mechanical ventilation including the use of positive end-expiratory pressure, recruitment maneuvers, and high frequency oscillatory ventilation are also addressed.

AB - Acute respiratory distress syndrome continues to be a high-mortality condition. The role of mechanical ventilation remains primarily a supportive modality. Recent research has elucidated the adverse impact of traditional ventilation strategies on development of the disease and, ultimately, mortality. The institution of low tidal volume ventilation has been the only intervention that has resulted in definitive improvement in survival. Animal and human investigations that culminated in the Acute Respiratory Distress Syndrome Network low tidal volume study are reviewed. Current controversies in the application of mechanical ventilation including the use of positive end-expiratory pressure, recruitment maneuvers, and high frequency oscillatory ventilation are also addressed.

KW - ARDS

KW - low tidal volumes

KW - lung protective strategies

KW - mechanical ventilation

UR - http://www.scopus.com/inward/record.url?scp=33744921085&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=33744921085&partnerID=8YFLogxK

U2 - 10.1053/j.semtcvs.2006.01.002

DO - 10.1053/j.semtcvs.2006.01.002

M3 - Article

C2 - 16766247

AN - SCOPUS:33744921085

VL - 18

SP - 8

EP - 12

JO - Seminars in Thoracic and Cardiovascular Surgery

JF - Seminars in Thoracic and Cardiovascular Surgery

SN - 1043-0679

IS - 1

ER -