Medullary sponge kidney and urinary calculi

Aeromedical concerns

Jeffrey A. Jones, Sebastian F. Cherian, Yael R. Barr, Amber Stocco

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Medullary sponge kidney (MSK) is a benign disorder associated with a lifetime risk of renal stones in 60% of patients. Patients frequently have episodic painless hematuria, but are often otherwise asymptomatic unless renal calculi or infections complicate the disease. Nephrolithiasis is a relative, but frequently enforced, contraindication to space or other high-performance flight. Two case reports of asymptomatic NASA flight crew with MSK and three cases of United States Air Force (USAF) military aviators diagnosed with MSK are reviewed. All cases resulted in waiver and return to flight status after treatment and a vigorous follow-up and prophylaxis protocol. MSK in aviation and spaceflight necessitates case-by-case evaluation and treatment to rule out other potential confounding factors that might also contribute to stone formation and in order to requalify the aviator for flight duties.

Original languageEnglish (US)
Pages (from-to)707-711
Number of pages5
JournalAviation Space and Environmental Medicine
Volume79
Issue number7
DOIs
StatePublished - Jul 2008

Fingerprint

Medullary Sponge Kidney
Aviators
Urinary Calculi
Kidney Calculi
Flight dynamics
Aviation
NASA
United States National Aeronautics and Space Administration
Nephrolithiasis
Space Flight
Hematuria
Air
Kidney
Therapeutics
Infection

Keywords

  • Aerospace medicine
  • Nephrolithiasis
  • Sponge kidney
  • Weightlessness

ASJC Scopus subject areas

  • Public Health, Environmental and Occupational Health
  • Pollution
  • Medicine(all)

Cite this

Medullary sponge kidney and urinary calculi : Aeromedical concerns. / Jones, Jeffrey A.; Cherian, Sebastian F.; Barr, Yael R.; Stocco, Amber.

In: Aviation Space and Environmental Medicine, Vol. 79, No. 7, 07.2008, p. 707-711.

Research output: Contribution to journalArticle

Jones, Jeffrey A. ; Cherian, Sebastian F. ; Barr, Yael R. ; Stocco, Amber. / Medullary sponge kidney and urinary calculi : Aeromedical concerns. In: Aviation Space and Environmental Medicine. 2008 ; Vol. 79, No. 7. pp. 707-711.
@article{bf8b4b05e66247acbe586da8f95ab39f,
title = "Medullary sponge kidney and urinary calculi: Aeromedical concerns",
abstract = "Medullary sponge kidney (MSK) is a benign disorder associated with a lifetime risk of renal stones in 60{\%} of patients. Patients frequently have episodic painless hematuria, but are often otherwise asymptomatic unless renal calculi or infections complicate the disease. Nephrolithiasis is a relative, but frequently enforced, contraindication to space or other high-performance flight. Two case reports of asymptomatic NASA flight crew with MSK and three cases of United States Air Force (USAF) military aviators diagnosed with MSK are reviewed. All cases resulted in waiver and return to flight status after treatment and a vigorous follow-up and prophylaxis protocol. MSK in aviation and spaceflight necessitates case-by-case evaluation and treatment to rule out other potential confounding factors that might also contribute to stone formation and in order to requalify the aviator for flight duties.",
keywords = "Aerospace medicine, Nephrolithiasis, Sponge kidney, Weightlessness",
author = "Jones, {Jeffrey A.} and Cherian, {Sebastian F.} and Barr, {Yael R.} and Amber Stocco",
year = "2008",
month = "7",
doi = "10.3357/ASEM.2255.2008",
language = "English (US)",
volume = "79",
pages = "707--711",
journal = "Aerospace medicine and human performance",
issn = "2375-6314",
publisher = "Aerospace Medical Association",
number = "7",

}

TY - JOUR

T1 - Medullary sponge kidney and urinary calculi

T2 - Aeromedical concerns

AU - Jones, Jeffrey A.

AU - Cherian, Sebastian F.

AU - Barr, Yael R.

AU - Stocco, Amber

PY - 2008/7

Y1 - 2008/7

N2 - Medullary sponge kidney (MSK) is a benign disorder associated with a lifetime risk of renal stones in 60% of patients. Patients frequently have episodic painless hematuria, but are often otherwise asymptomatic unless renal calculi or infections complicate the disease. Nephrolithiasis is a relative, but frequently enforced, contraindication to space or other high-performance flight. Two case reports of asymptomatic NASA flight crew with MSK and three cases of United States Air Force (USAF) military aviators diagnosed with MSK are reviewed. All cases resulted in waiver and return to flight status after treatment and a vigorous follow-up and prophylaxis protocol. MSK in aviation and spaceflight necessitates case-by-case evaluation and treatment to rule out other potential confounding factors that might also contribute to stone formation and in order to requalify the aviator for flight duties.

AB - Medullary sponge kidney (MSK) is a benign disorder associated with a lifetime risk of renal stones in 60% of patients. Patients frequently have episodic painless hematuria, but are often otherwise asymptomatic unless renal calculi or infections complicate the disease. Nephrolithiasis is a relative, but frequently enforced, contraindication to space or other high-performance flight. Two case reports of asymptomatic NASA flight crew with MSK and three cases of United States Air Force (USAF) military aviators diagnosed with MSK are reviewed. All cases resulted in waiver and return to flight status after treatment and a vigorous follow-up and prophylaxis protocol. MSK in aviation and spaceflight necessitates case-by-case evaluation and treatment to rule out other potential confounding factors that might also contribute to stone formation and in order to requalify the aviator for flight duties.

KW - Aerospace medicine

KW - Nephrolithiasis

KW - Sponge kidney

KW - Weightlessness

UR - http://www.scopus.com/inward/record.url?scp=46249112951&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=46249112951&partnerID=8YFLogxK

U2 - 10.3357/ASEM.2255.2008

DO - 10.3357/ASEM.2255.2008

M3 - Article

VL - 79

SP - 707

EP - 711

JO - Aerospace medicine and human performance

JF - Aerospace medicine and human performance

SN - 2375-6314

IS - 7

ER -