Melanoma

Norma E. Farrow; Aaron Therien; Douglas S. Tyler; Georgia M. Beasley

doi:10.1016/B978-0-12-800684-9.00005-8

Melanoma

Norma E. Farrow, Aaron Therien, Douglas S. Tyler, Georgia M. Beasley

Surgery

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Abstract

The treatment landscape for melanoma has dramatically changed in the last 9 years. The application of checkpoint blockade therapy and targeted therapies has driven improvements in survival for many patients with metastatic melanoma. Here, we review common molecular events that drive melanoma oncogenesis and review current molecular analysis that can guide individualized treatment plans.

Original language	English (US)
Title of host publication	Genomic and Precision Medicine
Subtitle of host publication	Oncology, Third Edition
Publisher	Elsevier
Pages	319-331
Number of pages	13
ISBN (Electronic)	9780128006849
ISBN (Print)	9780128006535
DOIs	https://doi.org/10.1016/B978-0-12-800684-9.00005-8
State	Published - Jan 1 2022

Keywords

BRAF mutation
Melanoma
immune therapy

ASJC Scopus subject areas

General Biochemistry, Genetics and Molecular Biology

Access to Document

10.1016/B978-0-12-800684-9.00005-8

Cite this

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title = "Melanoma",

abstract = "The treatment landscape for melanoma has dramatically changed in the last 9 years. The application of checkpoint blockade therapy and targeted therapies has driven improvements in survival for many patients with metastatic melanoma. Here, we review common molecular events that drive melanoma oncogenesis and review current molecular analysis that can guide individualized treatment plans.",

keywords = "BRAF mutation, Melanoma, immune therapy",

author = "Farrow, {Norma E.} and Aaron Therien and Tyler, {Douglas S.} and Beasley, {Georgia M.}",

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AU - Farrow, Norma E.

AU - Therien, Aaron

AU - Tyler, Douglas S.

AU - Beasley, Georgia M.

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N2 - The treatment landscape for melanoma has dramatically changed in the last 9 years. The application of checkpoint blockade therapy and targeted therapies has driven improvements in survival for many patients with metastatic melanoma. Here, we review common molecular events that drive melanoma oncogenesis and review current molecular analysis that can guide individualized treatment plans.

AB - The treatment landscape for melanoma has dramatically changed in the last 9 years. The application of checkpoint blockade therapy and targeted therapies has driven improvements in survival for many patients with metastatic melanoma. Here, we review common molecular events that drive melanoma oncogenesis and review current molecular analysis that can guide individualized treatment plans.

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KW - Melanoma

KW - immune therapy

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DO - 10.1016/B978-0-12-800684-9.00005-8

M3 - Chapter

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SP - 319

EP - 331

BT - Genomic and Precision Medicine

PB - Elsevier

ER -

Melanoma

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

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