Mercadeo virus: A novel mosquito-specific flavivirus from Panama

Jean Paul Carrera, Hilda Guzman, Davis Beltrán, Yamilka Díaz, Sandra López-Vergès, Rolando Torres-Cosme, Vsevolod Popov, Steven Widen, Thomas Wood, Scott Weaver, Lorenzo Cáceres-Carrera, Nikos Vasilakis, Robert B. Tesh

Research output: Contribution to journalArticle

15 Scopus citations

Abstract

Viruses in the genus Flavivirus (family Flaviviridae) include many arthropod-borne viruses of public health and veterinary importance. However, during the past two decades an explosion of novel insect-specific flaviviruses (ISFs), some closely related to vertebrate pathogens, have been discovered. Although many flavivirus pathogens of vertebrates have been isolated from naturally infected mosquitoes in Panama, ISFs have not previously been reported from the country. This report describes the isolation and characterization of a novel ISF, tentatively named Mercadeo virus (MECDV), obtained from Culex spp. mosquitoes collected in Panama. Two MECDV isolates were sequenced and cluster phylogenetically with cell-fusing agent virus (CFAV) and Nakiwogo virus (NAKV) to form a distinct lineage within the insect-specific group of flaviviruses.

Original languageEnglish (US)
Pages (from-to)1014-1019
Number of pages6
JournalAmerican Journal of Tropical Medicine and Hygiene
Volume93
Issue number5
DOIs
StatePublished - Nov 4 2015

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ASJC Scopus subject areas

  • Parasitology
  • Infectious Diseases
  • Virology

Cite this

Carrera, J. P., Guzman, H., Beltrán, D., Díaz, Y., López-Vergès, S., Torres-Cosme, R., Popov, V., Widen, S., Wood, T., Weaver, S., Cáceres-Carrera, L., Vasilakis, N., & Tesh, R. B. (2015). Mercadeo virus: A novel mosquito-specific flavivirus from Panama. American Journal of Tropical Medicine and Hygiene, 93(5), 1014-1019. https://doi.org/10.4269/ajtmh.15-0117