@article{8100359680274e36924c85e6681d66ec,
title = "Metabolic programming of macrophage functions and pathogens control",
abstract = "Macrophages (Mφ)are central players in mediating proinflammatory and immunomodulatory functions. Unchecked Mφ activities contribute to pathology across many diseases, including those caused by infectious pathogens and metabolic disorders. A fine balance of Mφ responses is crucial, which may be achieved by enforcing appropriate bioenergetics pathways. Metabolism serves as the provider of energy, substrates, and byproducts that support differential Mφ characteristics. The metabolic properties that control the polarization and response of Mφ remain to be fully uncovered for use in managing infectious diseases. Here, we review the various metabolic states in Mφ and how they influence the cell function.",
author = "Koo, {Sue jie} and Garg, {Nisha J.}",
note = "Funding Information: This work was supported in part by grants from the National Institute of Allergy and Infectious Diseases ( R01AI054578 ; R01AI136031 ) of the National Institutes of Health to NJG. A mini-center pilot grant (to NJG ) from the Institute for Human Infections and Immunity ( IHII ), UTMB , Galveston also supported part of the presented studies. SK was the recipient of pre-doctoral fellowships from the American Heart Association and the McLaughlin Endowment, IHII, UTMB. Funding Information: This work was supported in part by grants from the National Institute of Allergy and Infectious Diseases (R01AI054578; R01AI136031)of the National Institutes of Health to NJG. A mini-center pilot grant (to NJG)from the Institute for Human Infections and Immunity (IHII), UTMB, Galveston also supported part of the presented studies. SK was the recipient of pre-doctoral fellowships from the American Heart Association and the McLaughlin Endowment, IHII, UTMB. Publisher Copyright: {\textcopyright} 2019 The Authors",
year = "2019",
month = jun,
doi = "10.1016/j.redox.2019.101198",
language = "English (US)",
volume = "24",
journal = "Redox Biology",
issn = "2213-2317",
publisher = "Elsevier BV",
}