Metabolic rate alterations in early excision and grafting versus conservative treatment

T. C. Rutan, David Herndon, T. Van Osten, S. Abston

Research output: Contribution to journalArticle

44 Citations (Scopus)

Abstract

This study was done to determine whether early massive excision and grafting would decrease the hypermetabolic response that characterizes burn injury. Thirteen consecutively admitted adult males with burns over more than 45% of the total body surface area (TBSA) were randomly assigned to one of two treatment groups. One group was treated by excising the burn within 72 hours of injury and grafting with autograft overlaid with cadaveric allograft or cadaveric allograft alone depending on available donor sites and size of recipient areas. The second group was treated conservatively with daily hydrotherapy and twice daily applications of topical antimicrobial agents until granulating beds could receive autografts. Resting energy expenditure (REE) was calculated from measurement of vO2 and vCO2 at the patient's bedside. The responses of the two groups were comparable: the REE was approximately 20-30% above the predicted basal metabolic rate (BMR). Excisional therapy did not markedly decrease the hypermetabolic response to burn injury.

Original languageEnglish (US)
Pages (from-to)140-142
Number of pages3
JournalJournal of Trauma
Volume26
Issue number2
StatePublished - 1986

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Autografts
Energy Metabolism
Allografts
Wounds and Injuries
Hydrotherapy
Basal Metabolism
Body Surface Area
Anti-Infective Agents
Burns
Tissue Donors
Therapeutics
Conservative Treatment

ASJC Scopus subject areas

  • Surgery

Cite this

Rutan, T. C., Herndon, D., Van Osten, T., & Abston, S. (1986). Metabolic rate alterations in early excision and grafting versus conservative treatment. Journal of Trauma, 26(2), 140-142.

Metabolic rate alterations in early excision and grafting versus conservative treatment. / Rutan, T. C.; Herndon, David; Van Osten, T.; Abston, S.

In: Journal of Trauma, Vol. 26, No. 2, 1986, p. 140-142.

Research output: Contribution to journalArticle

Rutan, TC, Herndon, D, Van Osten, T & Abston, S 1986, 'Metabolic rate alterations in early excision and grafting versus conservative treatment', Journal of Trauma, vol. 26, no. 2, pp. 140-142.
Rutan, T. C. ; Herndon, David ; Van Osten, T. ; Abston, S. / Metabolic rate alterations in early excision and grafting versus conservative treatment. In: Journal of Trauma. 1986 ; Vol. 26, No. 2. pp. 140-142.
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