Metabolism of 3-tert-Butyl-4-hydroxyanisole by Microsomal Fractions and Isolated Rat Hepatocytes

Keyphrases

• Metabolism 100%
• Microsomal Fraction 100%
• Isolated Rat Hepatocytes 100%
• 3-tert-Butyl-4-hydroxyanisole 100%
• Polar Metabolites 83%
• FerT 83%
• Covalently Bound 33%
• Cytochrome P450 (CYP450) 33%
• Steady State 33%
• Tert-butyl 33%
• Formation Rate 33%
• Rat Liver Microsomes 33%
• Glucuronide Conjugate 33%
• Sulfate Conjugates 33%
• Tert-butylhydroquinone 33%
• Isozymes 16%
• 4-fold 16%
• Active Metabolite 16%
• Nicotinamide Adenine Dinucleotide Phosphate (NADPH) 16%
• Reductase 16%
• Glutathione 16%
• Glutathione Conjugates 16%
• Steady-state Concentration 16%
• Phenobarbital 16%
• Glucuronide 16%
• Microsomes 16%
• Human Liver Microsomes 16%
• NADPH Oxidase Activity 16%
• Rat Lung 16%
• Quinones 16%
• Tert 16%
• Isolated Hepatocytes 16%
• Oxidation-reduction 16%
• Reduced Nicotinamide Adenine Dinucleotide 16%
• Conjugated Metabolites 16%
• Benzoflavone 16%
• Phenolic Antioxidants 16%

Pharmacology, Toxicology and Pharmaceutical Science

• Butylated Hydroxyanisole 100%
• Glucuronide 50%
• Glutathione 33%
• Cytochrome P450 33%
• Reduced Nicotinamide Adenine Dinucleotide Phosphate 33%
• Sulfate 33%
• Antioxidant 16%
• Active Metabolite 16%
• Oxidoreductase 16%
• Phenobarbital 16%
• Reduced Nicotinamide Adenine Dinucleotide Phosphate Oxidase 16%
• Beta-Naphthoflavone 16%
• Tert Butylhydroquinone 16%
• Isoenzyme 16%