Metapneumovirus and acute wheezing in children

Tuomas Jartti, Bernadette Van Den Hoogen, Roberto Garofalo, Albert D M E Osterhaus, Olli Ruuskanen

Research output: Contribution to journalArticle

232 Citations (Scopus)

Abstract

A new respiratory virus, human metapneumovirus, was recently identified. We detected this virus by PCR in ten (8%) of 132 consecutive children admitted to Turku Hospital, Finland, for acute expiratory wheezing (median age 7 months, range 4-25). The mean duration of hospital stay was 2.5 days (SD 1.6) and mean duration of respiratory symptoms was 19 days (8). The white blood cell count, C-reactive protein, and regulated upon activation, normal T-cell-expressed and T-cell-secreted (RANTES) concentrations in nasal secretion remained low, whereas interleukin 8 concentrations in nasal secretion were high. Human metapneumovirus is a clinically important causative agent of acute wheezing in young children.

Original languageEnglish (US)
Pages (from-to)1393-1394
Number of pages2
JournalLancet
Volume360
Issue number9343
DOIs
StatePublished - Nov 2 2002

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Metapneumovirus
Respiratory Sounds
Nose
Viruses
T-Lymphocytes
Finland
Interleukin-8
Leukocyte Count
C-Reactive Protein
Length of Stay
Polymerase Chain Reaction

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Jartti, T., Van Den Hoogen, B., Garofalo, R., Osterhaus, A. D. M. E., & Ruuskanen, O. (2002). Metapneumovirus and acute wheezing in children. Lancet, 360(9343), 1393-1394. https://doi.org/10.1016/S0140-6736(02)11391-2

Metapneumovirus and acute wheezing in children. / Jartti, Tuomas; Van Den Hoogen, Bernadette; Garofalo, Roberto; Osterhaus, Albert D M E; Ruuskanen, Olli.

In: Lancet, Vol. 360, No. 9343, 02.11.2002, p. 1393-1394.

Research output: Contribution to journalArticle

Jartti, T, Van Den Hoogen, B, Garofalo, R, Osterhaus, ADME & Ruuskanen, O 2002, 'Metapneumovirus and acute wheezing in children', Lancet, vol. 360, no. 9343, pp. 1393-1394. https://doi.org/10.1016/S0140-6736(02)11391-2
Jartti T, Van Den Hoogen B, Garofalo R, Osterhaus ADME, Ruuskanen O. Metapneumovirus and acute wheezing in children. Lancet. 2002 Nov 2;360(9343):1393-1394. https://doi.org/10.1016/S0140-6736(02)11391-2
Jartti, Tuomas ; Van Den Hoogen, Bernadette ; Garofalo, Roberto ; Osterhaus, Albert D M E ; Ruuskanen, Olli. / Metapneumovirus and acute wheezing in children. In: Lancet. 2002 ; Vol. 360, No. 9343. pp. 1393-1394.
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