Methods for determining blood flow in the brain — Part I: Review of several cerebral blood flow techniques

Abund O. Wist; Panos P. Fatouros; P. R.S. Kishore; Douglas S. Dewitt; Richard L. Keenan; Gopala U. Rao; J. Paul Muizelaar; Geoffrey D. Clarke; Lauraine Stewart; Anthony Marmarou; Hermes A. Kontos

doi:10.1097/00004669-198701000-00010

Methods for determining blood flow in the brain — Part I: Review of several cerebral blood flow techniques

Abund O. Wist, Panos P. Fatouros, P. R.S. Kishore, Douglas S. Dewitt, Richard L. Keenan, Gopala U. Rao, J. Paul Muizelaar, Geoffrey D. Clarke, Lauraine Stewart, Anthony Marmarou, Hermes A. Kontos

Research output: Contribution to journal › Article › peer-review

Abstract

Knowledge of absolute cerebral blood flow (CBF) values is important in the diagnosis and treatment of many pathologies of the brain, such as stroke, aneurysms, and degenerative diseases. In this paper, the more important, noninvasive CBF techniques used clinically or deemed promising for future use are reviewed. These are: the radioactive xenon-133 method, the stable xenon/CT method, positron emission tomography, and magnetic resonance imaging. In addition, the radiolabeled microsphere technique, which is an invasive method, is discussed because of its established role as a standard of reference. Each method is described briefly, and its advantages and disadvantages are outlined.

Original language	English (US)
Pages (from-to)	49-56
Number of pages	8
Journal	Journal of Clinical Engineering
Volume	12
Issue number	1
DOIs	https://doi.org/10.1097/00004669-198701000-00010
State	Published - 1987
Externally published	Yes

Keywords

Brain, blood flow
Cerebral blood flow
Magnetic resonance imaging
Positron emission tomography
Radioactive xenon-133 CBF technique
Radiolabeled microsphere CBF technique
Xenon/CT CBF method

ASJC Scopus subject areas

Medicine (miscellaneous)
Biomedical Engineering

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10.1097/00004669-198701000-00010

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Wist, A. O., Fatouros, P. P., Kishore, P. R. S., Dewitt, D. S., Keenan, R. L., Rao, G. U., Muizelaar, J. P., Clarke, G. D., Stewart, L., Marmarou, A., & Kontos, H. A. (1987). Methods for determining blood flow in the brain — Part I: Review of several cerebral blood flow techniques. Journal of Clinical Engineering, 12(1), 49-56. https://doi.org/10.1097/00004669-198701000-00010

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title = "Methods for determining blood flow in the brain — Part I: Review of several cerebral blood flow techniques",

abstract = "Knowledge of absolute cerebral blood flow (CBF) values is important in the diagnosis and treatment of many pathologies of the brain, such as stroke, aneurysms, and degenerative diseases. In this paper, the more important, noninvasive CBF techniques used clinically or deemed promising for future use are reviewed. These are: the radioactive xenon-133 method, the stable xenon/CT method, positron emission tomography, and magnetic resonance imaging. In addition, the radiolabeled microsphere technique, which is an invasive method, is discussed because of its established role as a standard of reference. Each method is described briefly, and its advantages and disadvantages are outlined.",

keywords = "Brain, blood flow, Cerebral blood flow, Magnetic resonance imaging, Positron emission tomography, Radioactive xenon-133 CBF technique, Radiolabeled microsphere CBF technique, Xenon/CT CBF method",

author = "Wist, {Abund O.} and Fatouros, {Panos P.} and Kishore, {P. R.S.} and Dewitt, {Douglas S.} and Keenan, {Richard L.} and Rao, {Gopala U.} and Muizelaar, {J. Paul} and Clarke, {Geoffrey D.} and Lauraine Stewart and Anthony Marmarou and Kontos, {Hermes A.}",

year = "1987",

doi = "10.1097/00004669-198701000-00010",

language = "English (US)",

volume = "12",

pages = "49--56",

journal = "Journal of Clinical Engineering",

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publisher = "Lippincott Williams and Wilkins",

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TY - JOUR

T1 - Methods for determining blood flow in the brain — Part I

T2 - Review of several cerebral blood flow techniques

AU - Wist, Abund O.

AU - Fatouros, Panos P.

AU - Kishore, P. R.S.

AU - Dewitt, Douglas S.

AU - Keenan, Richard L.

AU - Rao, Gopala U.

AU - Muizelaar, J. Paul

AU - Clarke, Geoffrey D.

AU - Stewart, Lauraine

AU - Marmarou, Anthony

AU - Kontos, Hermes A.

PY - 1987

Y1 - 1987

N2 - Knowledge of absolute cerebral blood flow (CBF) values is important in the diagnosis and treatment of many pathologies of the brain, such as stroke, aneurysms, and degenerative diseases. In this paper, the more important, noninvasive CBF techniques used clinically or deemed promising for future use are reviewed. These are: the radioactive xenon-133 method, the stable xenon/CT method, positron emission tomography, and magnetic resonance imaging. In addition, the radiolabeled microsphere technique, which is an invasive method, is discussed because of its established role as a standard of reference. Each method is described briefly, and its advantages and disadvantages are outlined.

AB - Knowledge of absolute cerebral blood flow (CBF) values is important in the diagnosis and treatment of many pathologies of the brain, such as stroke, aneurysms, and degenerative diseases. In this paper, the more important, noninvasive CBF techniques used clinically or deemed promising for future use are reviewed. These are: the radioactive xenon-133 method, the stable xenon/CT method, positron emission tomography, and magnetic resonance imaging. In addition, the radiolabeled microsphere technique, which is an invasive method, is discussed because of its established role as a standard of reference. Each method is described briefly, and its advantages and disadvantages are outlined.

KW - Brain, blood flow

KW - Cerebral blood flow

KW - Magnetic resonance imaging

KW - Positron emission tomography

KW - Radioactive xenon-133 CBF technique

KW - Radiolabeled microsphere CBF technique

KW - Xenon/CT CBF method

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JO - Journal of Clinical Engineering

JF - Journal of Clinical Engineering

IS - 1

ER -

Methods for determining blood flow in the brain — Part I: Review of several cerebral blood flow techniques

Abstract

Keywords

ASJC Scopus subject areas

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