Microbial control of arthropod-borne disease

Miguel A. Saldaña, Shivanand Hegde, Grant L. Hughes

Research output: Contribution to journalArticlepeer-review

44 Scopus citations


Arthropods harbor a diverse array of microbes that profoundly influence many aspects of host biology, including vector competence. Additionally, symbionts can be engineered to produce molecules that inhibit pathogens. Due to their intimate association with the host, microbes have developed strategies that facilitate their transmission, either horizontally or vertically, to conspecifics. These attributes make microbes attractive agents for applied strategies to control arthropod-borne disease. Here we discuss the recent advances in microbial control approaches to reduce the burden of pathogens such as Zika, Dengue and Chikungunya viruses, and Trypanosome and Plasmodium parasites. We also highlight where further investigation is warranted.

Original languageEnglish (US)
Pages (from-to)81-93
Number of pages13
JournalMemorias do Instituto Oswaldo Cruz
Issue number2
StatePublished - Feb 2017


  • Arbovirus
  • Malaria
  • Microbiome
  • Mosquito
  • Paratransgenesis
  • Vector control

ASJC Scopus subject areas

  • Microbiology (medical)


Dive into the research topics of 'Microbial control of arthropod-borne disease'. Together they form a unique fingerprint.

Cite this