Microbial sealants do not decrease surgical site infection for clean-contaminated colorectal procedures

M. Doorly, J. Choi, A. Floyd, A. Senagore

Research output: Contribution to journalArticle

3 Scopus citations


Background: Surgical site infections (SSI) are costly complications that may cause significant morbidity and increase the cost of care, particularly in colorectal surgery. Microbial sealants (MS) are a new class of wound barriers aimed at decreasing SSI; however, there is only evidence of benefit in clean class 1 procedures. Based on its success in class 1 procedures, we hypothesized that a microbial sealant could reduce the rate of SSI by half for clean-contaminated colorectal procedures (class 2). Methods: This was a single institution, multihospital, prospective, randomized study approved by the institutional review board. The primary objective was to determine the rate of SSI when microbial sealant (InteguSeal

Original languageEnglish (US)
Pages (from-to)281-285
Number of pages5
JournalTechniques in Coloproctology
Issue number5
StatePublished - May 1 2015
Externally publishedYes



  • Colorectal surgery
  • SSI
  • Wound barrier

ASJC Scopus subject areas

  • Gastroenterology
  • Surgery
  • Medicine(all)

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