Microbiota regulation of inflammatory bowel disease

Heather L. Evans-Marin, Yingzi Cong

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

The intestines harbor over trillions of commensal bacteria, which co-evolve and form a mutualistic relationship with the host, with microbial-host interaction shaping immune adaption and bacterial communities. The intestinal microbiota not only benefits the host and contributes to the maintenance of intestinal homeostasis, but also causes chronic intestinal inflammation under certain conditions. Thus, understanding the microbiota regulation of inflammatory bowel disease (IBD) will provide great insights into the pathogenesis of IBD as well as potential therapeutics for IBD patients.

Original languageEnglish (US)
Pages (from-to)65-73
Number of pages9
JournalInflammation and Allergy - Drug Targets
Volume13
Issue number1
DOIs
StatePublished - 2014

Fingerprint

Microbiota
Inflammatory Bowel Diseases
Microbial Interactions
Intestines
Homeostasis
Maintenance
Inflammation
Bacteria
Therapeutics

Keywords

  • IBD
  • Intestines
  • Microbiota
  • Probiotics
  • T cells

ASJC Scopus subject areas

  • Immunology
  • Immunology and Allergy
  • Pharmacology

Cite this

Microbiota regulation of inflammatory bowel disease. / Evans-Marin, Heather L.; Cong, Yingzi.

In: Inflammation and Allergy - Drug Targets, Vol. 13, No. 1, 2014, p. 65-73.

Research output: Contribution to journalArticle

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