Microbiota regulation of inflammatory bowel disease

Heather L. Evans-Marin, Yingzi Cong

Research output: Contribution to journalArticle

1 Scopus citations

Abstract

The intestines harbor over trillions of commensal bacteria, which co-evolve and form a mutualistic relationship with the host, with microbial-host interaction shaping immune adaption and bacterial communities. The intestinal microbiota not only benefits the host and contributes to the maintenance of intestinal homeostasis, but also causes chronic intestinal inflammation under certain conditions. Thus, understanding the microbiota regulation of inflammatory bowel disease (IBD) will provide great insights into the pathogenesis of IBD as well as potential therapeutics for IBD patients.

Original languageEnglish (US)
Pages (from-to)65-73
Number of pages9
JournalInflammation and Allergy - Drug Targets
Volume13
Issue number1
DOIs
StatePublished - Jan 1 2014

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Keywords

  • IBD
  • Intestines
  • Microbiota
  • Probiotics
  • T cells

ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology
  • Pharmacology

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