Microsurgical Management of Intracranial Aneurysms After Failed Flow Diversion

Nnenna Mbabuike, Sophia F. Shakur, Kelly Gassie, Visish Srinivasan, Justin Mascitelli, Adib Abla, Edward Duckworth, Peter Kan, Georgios A. Zenonos, Clemens Schirmer, Fady T. Charbel, Evandro de Olivera, Jacques J. Morcos, Michael Lawton, Rabih G. Tawk

Research output: Contribution to journalArticlepeer-review

7 Scopus citations


Background: Flow diversion has become increasingly popular for treatment of cerebral aneurysms in the past few years. In an increasing number of patients with aneurysms, flow diversion (FD) has failed, with a paucity of reported data regarding salvage treatment for these challenging cases. Methods: We present a multicenter series of 13 aneurysms for which FD failed and that were subsequently treated with open surgery. We also present a review of the reported data regarding operative management of aneurysms after unsuccessful FD. Results: Twelve patients with 13 aneurysms were included in the present study. All 12 patients had undergone surgery after FD because of persistent aneurysm filling, mass effect, or aneurysm rupture. The patients underwent aneurysm clipping and parent vessel reconstruction, decompression of the aneurysm mass, occlusion of proximal flow to the aneurysm, or aneurysm trapping with or without extracranial–intracranial artery bypass. Conclusions: Aneurysms for which FD fails present a variety of unique and challenging management situations that will likely be encountered with increased frequency, given the popularity of FD. Microsurgical salvage options require individualized care tailored to the underlying pathological features, patient characteristics, and surgical expertise.

Original languageEnglish (US)
Pages (from-to)e16-e28
JournalWorld Neurosurgery
StatePublished - Feb 2020
Externally publishedYes


  • Aneurysms
  • Bailout
  • Flow diversion
  • Microsurgery
  • Operative
  • Treatment

ASJC Scopus subject areas

  • Surgery
  • Clinical Neurology


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