Middle east respiratory syndrome vaccine candidates: Cautious optimism

Craig Schindewolf, Vineet D. Menachery

Research output: Contribution to journal › Review article › peer-review

30 Scopus citations

Abstract

Efforts towards developing a vaccine for Middle East respiratory syndrome coronavirus (MERS-CoV) have yielded promising results. Utilizing a variety of platforms, several vaccine approaches have shown efficacy in animal models and begun to enter clinical trials. In this review, we summarize the current progress towards a MERS-CoV vaccine and highlight potential roadblocks identified from previous attempts to generate coronavirus vaccines.

Original languageEnglish (US)
Article number74
JournalViruses
Volume11
Issue number1
DOIs
StatePublished - Jan 1 2019

Keywords

  • Animal models
  • Coronavirus spike glycoprotein
  • Correlates of immunity
  • Middle East respiratory syndrome coronavirus
  • Severe acute respiratory syndrome coronavirus
  • Vaccine platforms

ASJC Scopus subject areas

  • Infectious Diseases
  • Virology

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