Middle East Respiratory Syndrome Vaccine Candidates: Cautious Optimism

Craig Schindewolf, Vineet Menachery

Research output: Contribution to journalReview article

15 Scopus citations

Abstract

Efforts towards developing a vaccine for Middle East respiratory syndrome coronavirus (MERS-CoV) have yielded promising results. Utilizing a variety of platforms, several vaccine approaches have shown efficacy in animal models and begun to enter clinical trials. In this review, we summarize the current progress towards a MERS-CoV vaccine and highlight potential roadblocks identified from previous attempts to generate coronavirus vaccines.

Original languageEnglish (US)
JournalViruses
Volume11
Issue number1
DOIs
StatePublished - Jan 17 2019

Keywords

  • animal models
  • coronavirus spike glycoprotein
  • correlates of immunity
  • Middle East respiratory syndrome coronavirus
  • severe acute respiratory syndrome coronavirus
  • vaccine platforms

ASJC Scopus subject areas

  • Infectious Diseases
  • Virology

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