MIIP remodels Rac1-mediated cytoskeleton structure in suppression of endometrial cancer metastasis

Biochemistry, Genetics and Molecular Biology

• Cytoskeleton 100%
• PAK1 100%
• Cell Migration 80%
• Protein Expression 60%
• Binding Domain 40%
• Guanosine Triphosphate 40%
• Small Interfering RNA 40%
• Actin 20%
• Immunoprecipitation 20%
• Protein Interaction 20%
• Protein Expression Level 20%
• Immunofluorescence 20%
• Cell Invasion 20%
• C-Terminus 20%
• Tumor Suppressor Gene 20%
• P21 20%
• Staining 20%
• Chromosome 20%
• Filopodia 20%
• Reproductive System 20%

Keyphrases

• Inhibitory Proteins 100%
• Rac1 100%
• Cytoskeleton Structure 100%
• Endometrial Carcinoma 47%
• PAK1 26%
• Cell Migration 21%
• Protein Expression 15%
• Small Interfering RNA (siRNA) 10%
• Ligand-binding Domain 10%
• Gain-of-function 10%
• Tumor Suppressor Gene 10%
• Loss Function 10%
• Rac1 Signaling 10%
• Endometrial Carcinoma Cells 10%
• Carcinoma Metastasis 10%
• Advanced Stage 5%
• Co-immunoprecipitation (co-IP) 5%
• Immunohistochemistry 5%
• Protein-coding Genes 5%
• Tumor 5%
• Cell Morphology 5%
• Malignancy 5%
• Filamentous Actin (F-actin) 5%
• Cell Invasion 5%
• Signaling Cascades 5%
• Immunofluorescence Staining 5%
• Lymph Node Metastasis 5%
• Activity Assay 5%
• Rac1-GTP 5%
• Protein Expression Level 5%
• Inhibiting Activity 5%
• Female Reproductive System 5%
• Invasion Pathways 5%
• Transwell Assay 5%
• 1p36 Deletion 5%
• Lamellipodia 5%
• Polyproline 5%
• Migration Mechanism 5%
• Protein-protein Interaction Network 5%
• Interaction Loss 5%
• Deep Myometrial Invasion 5%
• Assay Kits 5%
• Cytoskeletal Remodeling 5%
• Reduced Cells 5%