Modeling fluid structure-interactions for biomechanical analysis of the human eye

Edward P. Furlani, Anthony Nunez, Gianmarco Vizzeri

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Citation (Scopus)

Abstract

A method is presented for studying and quantifying the biomechanical behavior of the human eye under elevated fluid and structural pressure loading. The approach taken involves a coupled synergistic computer modeling and experimental effort in which numerical models are used to predict the biomechanical response of eye under pressure, and physical cadaveric eye models along with appropriate imaging modalities are used to validate the theoretical predictions of tissue deformation within the eye. The numerical models are based on computational fluid dynamic (CFD) analysis combined wim a fully-coupled fluid-structure interaction (FSI) capability. Preliminary numerical modeling results of pressure-induced tissue deformation are demonstrated via application to an idealized eye geometry. A discussion is given of challenges and opportunities of using this approach to advance understanding of biomechanical behavior of the human eye.

Original languageEnglish (US)
Title of host publicationTechnical Proceedings of the 2012 NSTI Nanotechnology Conference and Expo, NSTI-Nanotech 2012
Pages337-340
Number of pages4
StatePublished - 2012
EventNanotechnology 2012: Electronics, Devices, Fabrication, MEMS, Fluidics and Computational - 2012 NSTI Nanotechnology Conference and Expo, NSTI-Nanotech 2012 - Santa Clara, CA, United States
Duration: Jun 18 2012Jun 21 2012

Other

OtherNanotechnology 2012: Electronics, Devices, Fabrication, MEMS, Fluidics and Computational - 2012 NSTI Nanotechnology Conference and Expo, NSTI-Nanotech 2012
CountryUnited States
CitySanta Clara, CA
Period6/18/126/21/12

Fingerprint

Fluid structure interaction
Numerical models
Tissue
Dynamic analysis
Computational fluid dynamics
Imaging techniques
Fluids
Geometry

Keywords

  • Astronaut ocular abnormalities
  • Biomechanics of the eye
  • Fluid structure interactions
  • Intraocular pressure
  • Optic nerve stress
  • Stress and strain of eye tissue

ASJC Scopus subject areas

  • Ceramics and Composites
  • Surfaces, Coatings and Films

Cite this

Furlani, E. P., Nunez, A., & Vizzeri, G. (2012). Modeling fluid structure-interactions for biomechanical analysis of the human eye. In Technical Proceedings of the 2012 NSTI Nanotechnology Conference and Expo, NSTI-Nanotech 2012 (pp. 337-340)

Modeling fluid structure-interactions for biomechanical analysis of the human eye. / Furlani, Edward P.; Nunez, Anthony; Vizzeri, Gianmarco.

Technical Proceedings of the 2012 NSTI Nanotechnology Conference and Expo, NSTI-Nanotech 2012. 2012. p. 337-340.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Furlani, EP, Nunez, A & Vizzeri, G 2012, Modeling fluid structure-interactions for biomechanical analysis of the human eye. in Technical Proceedings of the 2012 NSTI Nanotechnology Conference and Expo, NSTI-Nanotech 2012. pp. 337-340, Nanotechnology 2012: Electronics, Devices, Fabrication, MEMS, Fluidics and Computational - 2012 NSTI Nanotechnology Conference and Expo, NSTI-Nanotech 2012, Santa Clara, CA, United States, 6/18/12.
Furlani EP, Nunez A, Vizzeri G. Modeling fluid structure-interactions for biomechanical analysis of the human eye. In Technical Proceedings of the 2012 NSTI Nanotechnology Conference and Expo, NSTI-Nanotech 2012. 2012. p. 337-340
Furlani, Edward P. ; Nunez, Anthony ; Vizzeri, Gianmarco. / Modeling fluid structure-interactions for biomechanical analysis of the human eye. Technical Proceedings of the 2012 NSTI Nanotechnology Conference and Expo, NSTI-Nanotech 2012. 2012. pp. 337-340
@inproceedings{17932b3d74b0447bb35a8bfd76be79af,
title = "Modeling fluid structure-interactions for biomechanical analysis of the human eye",
abstract = "A method is presented for studying and quantifying the biomechanical behavior of the human eye under elevated fluid and structural pressure loading. The approach taken involves a coupled synergistic computer modeling and experimental effort in which numerical models are used to predict the biomechanical response of eye under pressure, and physical cadaveric eye models along with appropriate imaging modalities are used to validate the theoretical predictions of tissue deformation within the eye. The numerical models are based on computational fluid dynamic (CFD) analysis combined wim a fully-coupled fluid-structure interaction (FSI) capability. Preliminary numerical modeling results of pressure-induced tissue deformation are demonstrated via application to an idealized eye geometry. A discussion is given of challenges and opportunities of using this approach to advance understanding of biomechanical behavior of the human eye.",
keywords = "Astronaut ocular abnormalities, Biomechanics of the eye, Fluid structure interactions, Intraocular pressure, Optic nerve stress, Stress and strain of eye tissue",
author = "Furlani, {Edward P.} and Anthony Nunez and Gianmarco Vizzeri",
year = "2012",
language = "English (US)",
isbn = "9781466562752",
pages = "337--340",
booktitle = "Technical Proceedings of the 2012 NSTI Nanotechnology Conference and Expo, NSTI-Nanotech 2012",

}

TY - GEN

T1 - Modeling fluid structure-interactions for biomechanical analysis of the human eye

AU - Furlani, Edward P.

AU - Nunez, Anthony

AU - Vizzeri, Gianmarco

PY - 2012

Y1 - 2012

N2 - A method is presented for studying and quantifying the biomechanical behavior of the human eye under elevated fluid and structural pressure loading. The approach taken involves a coupled synergistic computer modeling and experimental effort in which numerical models are used to predict the biomechanical response of eye under pressure, and physical cadaveric eye models along with appropriate imaging modalities are used to validate the theoretical predictions of tissue deformation within the eye. The numerical models are based on computational fluid dynamic (CFD) analysis combined wim a fully-coupled fluid-structure interaction (FSI) capability. Preliminary numerical modeling results of pressure-induced tissue deformation are demonstrated via application to an idealized eye geometry. A discussion is given of challenges and opportunities of using this approach to advance understanding of biomechanical behavior of the human eye.

AB - A method is presented for studying and quantifying the biomechanical behavior of the human eye under elevated fluid and structural pressure loading. The approach taken involves a coupled synergistic computer modeling and experimental effort in which numerical models are used to predict the biomechanical response of eye under pressure, and physical cadaveric eye models along with appropriate imaging modalities are used to validate the theoretical predictions of tissue deformation within the eye. The numerical models are based on computational fluid dynamic (CFD) analysis combined wim a fully-coupled fluid-structure interaction (FSI) capability. Preliminary numerical modeling results of pressure-induced tissue deformation are demonstrated via application to an idealized eye geometry. A discussion is given of challenges and opportunities of using this approach to advance understanding of biomechanical behavior of the human eye.

KW - Astronaut ocular abnormalities

KW - Biomechanics of the eye

KW - Fluid structure interactions

KW - Intraocular pressure

KW - Optic nerve stress

KW - Stress and strain of eye tissue

UR - http://www.scopus.com/inward/record.url?scp=84864956294&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84864956294&partnerID=8YFLogxK

M3 - Conference contribution

SN - 9781466562752

SP - 337

EP - 340

BT - Technical Proceedings of the 2012 NSTI Nanotechnology Conference and Expo, NSTI-Nanotech 2012

ER -