Modeling Zika Virus Infection in Mice

Shannan L. Rossi; Nikos Vasilakis

doi:10.1016/j.stem.2016.06.009

Modeling Zika Virus Infection in Mice

Pathology

Research output: Contribution to journal › Short survey › peer-review

24 Scopus citations

Abstract

Understanding the link between Zika virus (ZIKV) infection and microcephaly requires in vivo models of ZIKV infection in pregnant adults and fetuses. Three studies recently generated such mouse models of ZIKV infection, which corroborate previous in vitro evidence linking ZIKV infection and apoptosis induction in neurons and progenitors to microcephaly.

Original language	English (US)
Pages (from-to)	4-6
Number of pages	3
Journal	Cell Stem Cell
Volume	19
Issue number	1
DOIs	https://doi.org/10.1016/j.stem.2016.06.009
State	Published - Jul 1 2016

ASJC Scopus subject areas

Molecular Medicine
Genetics
Cell Biology

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10.1016/j.stem.2016.06.009

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title = "Modeling Zika Virus Infection in Mice",

abstract = "Understanding the link between Zika virus (ZIKV) infection and microcephaly requires in vivo models of ZIKV infection in pregnant adults and fetuses. Three studies recently generated such mouse models of ZIKV infection, which corroborate previous in vitro evidence linking ZIKV infection and apoptosis induction in neurons and progenitors to microcephaly.",

author = "Rossi, \{Shannan L.\} and Nikos Vasilakis",

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year = "2016",

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AU - Rossi, Shannan L.

AU - Vasilakis, Nikos

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N2 - Understanding the link between Zika virus (ZIKV) infection and microcephaly requires in vivo models of ZIKV infection in pregnant adults and fetuses. Three studies recently generated such mouse models of ZIKV infection, which corroborate previous in vitro evidence linking ZIKV infection and apoptosis induction in neurons and progenitors to microcephaly.

AB - Understanding the link between Zika virus (ZIKV) infection and microcephaly requires in vivo models of ZIKV infection in pregnant adults and fetuses. Three studies recently generated such mouse models of ZIKV infection, which corroborate previous in vitro evidence linking ZIKV infection and apoptosis induction in neurons and progenitors to microcephaly.

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UR - https://www.scopus.com/pages/publications/85008931779#tab=citedBy

U2 - 10.1016/j.stem.2016.06.009

DO - 10.1016/j.stem.2016.06.009

M3 - Short survey

C2 - 27392219

AN - SCOPUS:85008931779

SN - 1934-5909

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SP - 4

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JO - Cell Stem Cell

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Modeling Zika Virus Infection in Mice

Abstract

ASJC Scopus subject areas

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