Modulation of allostery of pyruvate kinase by shifting of an ensemble of microstates

Keyphrases

• Allostery 100%
• Pyruvate Kinase 100%
• Microstates 100%
• Conformational States 40%
• Structural Motif 40%
• Sequence Difference 40%
• Secondary Structural Elements 40%
• Protein Dynamics 20%
• Regulatory Mechanism 20%
• Structural Change 20%
• Differential Effects 20%
• Kinetic Data 20%
• Ligand Binding 20%
• Structure Function 20%
• Ligand Effects 20%
• Allosteric Regulation 20%
• Thermodynamic Data 20%
• Cooperativity 20%
• About Four 20%
• Domain Movement 20%
• Triosephosphate Isomerase 20%
• Solution Thermodynamics 20%
• Solution Kinetic 20%
• Enzyme-ligand Interaction 20%
• Chemical Principles 20%

Biochemistry, Genetics and Molecular Biology

• Allosteric Regulation 100%
• Pyruvate Kinase 100%
• Structural Motif 40%
• Dynamics 20%
• Solution and Solubility 20%
• Enzyme 20%
• Ligand Binding 20%
• Cooperation 20%
• Triosephosphate Isomerase 20%
• Protein Dynamics 20%