Mohs micrographic surgery

D. L. Shriner, D. K. McCoy, D. J. Goldberg, Jr Wagner

Research output: Contribution to journalArticlepeer-review

309 Scopus citations


Mohs micrographic surgery (MMS) is a specialized type of minimal marginal surgery that offers cure rates superior to other options in the treatment of contiguous skin cancers in selected settings. Developed by Dr. Frederic E. Mohs, the technique originally required in situ tissue fixation before excision. Most Mohs micrographic surgeons now use the fresh tissue technique exclusively. Horizontal frozen histologic sections of the excised tumor permit more complete microscopic examination of the surgical margin than traditional methods. Residual tumor is graphically mapped and malignant extensions are pursued with staged excisions until the tumor is removed. Maximum sparing of tumor-free adjacent tissue is achieved with histologic mapping of the tumor boundaries, thus optimizing subsequent wound reconstruction. The history, techniques, indications, cure rates, and current controversies of MMS are reviewed.

Original languageEnglish (US)
Pages (from-to)79-97
Number of pages19
JournalJournal of the American Academy of Dermatology
Issue number1
StatePublished - 1998

ASJC Scopus subject areas

  • Dermatology


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