Molecular analysis of hprt mutant lymphocytes from 1,3-butadiene-exposed workers

Keyphrases

• Lymphocytes 100%
• Hprt 100%
• Molecular Analysis 100%
• 1,3-Butadiene 100%
• Exposed Workers 100%
• Control Subjects 41%
• Genotoxic Effect 16%
• Exon Deletion 16%
• Molecular Mechanism 8%
• Complementary DNA (cDNA) 8%
• Structural Change 8%
• Sequence Analysis 8%
• Carcinogenicity 8%
• Butadiene 8%
• Repeated DNA Sequences 8%
• Mutational Spectrum 8%
• Mutant Frequency 8%
• Genotoxicity 8%
• Multiplex PCR (mPCR) 8%
• Single-base Substitution 8%
• N-11 8%
• Human Carcinogen 8%
• TK6 Cells 8%
• Transversion 8%
• Frameshift mutation 8%
• Spectral Changes 8%
• Animal Carcinogen 8%
• Mutation Type 8%
• Clonal Assays 8%

Biochemistry, Genetics and Molecular Biology

• Lymphocyte 100%
• Exon 66%
• Metabolite 33%
• Protein Sequencing 33%
• Repeated Sequence (DNA) 33%
• Nucleic Acid Base Substitution 33%
• Shotgun Sequencing 33%
• Multiplex Polymerase Chain Reaction 33%
• Frameshift Mutation 33%
• Transversion 33%

Pharmacology, Toxicology and Pharmaceutical Science

• Hypoxanthine Phosphoribosyltransferase 100%
• 1,3-Butadiene 100%
• Carcinogen 15%
• Biological Marker 7%
• Complementary DNA 7%
• Base 7%
• Carcinogenicity 7%
• Repetitive DNA 7%
• Genotoxicity 7%