Molecular basis of canavan’s disease: From human to mouse

Keyphrases

• Canavan Disease 100%
• Aspartoacylase 40%
• N-acetylneuraminic Acid 40%
• Knock-in Mouse Model 20%
• Pathophysiology 20%
• Clinical Features 20%
• Gene Transfer 20%
• New Therapies 20%
• Central Nervous System 20%
• White Matter 20%
• Jewish Population 20%
• Ashkenazi Jews 20%
• Brain Fluids 20%
• Myelin 20%
• Intellectual Disability 20%
• Autosomal Recessive 20%
• Body Fluids 20%
• Spasticity 20%
• Hypotonia 20%
• Spongy Degeneration 20%
• Macrocephaly 20%
• Aspartoacylase Deficiency 20%

Neuroscience

• Canavan Disease 100%
• Aspartoacylase 60%
• N-Acetylaspartic Acid 40%
• Central Nervous System 20%
• Gene Transfer 20%
• Gene Delivery 20%
• Myelin 20%
• Autosomal Recessive Disorder 20%
• Hypotonia 20%
• Macrocephaly 20%

Biochemistry, Genetics and Molecular Biology

• Canavan Disease 100%
• Aspartoacylase 60%
• Enzymatic Hydrolysis 20%
• Knockout Mouse 20%
• Liquid 20%
• Autosomal Recessive Disorder 20%
• Myelin 20%