Abstract
In this review, cisplatin resistance will be summarized. We will discuss characteristics of potential mechanisms of resistance in tissues from patients with ovarian, colon and breast carcinoma. Secondly, a new molecular biology assay will be discussed which detects changes in gene expression in cisplatin-resistant cells. Finally, based on the biochemical and molecular properties of cisplatin-resistant tumors, new strategies to exploit or circumvent cisplatin resistance in human tumors wil be entertained.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 1301-1312 |
| Number of pages | 12 |
| Journal | Anticancer Research |
| Volume | 9 |
| Issue number | 5 |
| State | Published - 1989 |
| Externally published | Yes |
ASJC Scopus subject areas
- Oncology
- Cancer Research
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