TY - JOUR
T1 - Molecular confirmation of sappinia pedata as a causative agent of amoebic encephalitis
AU - Qvarnstrom, Yvonne
AU - Da Silva, Alexandre J.
AU - Schuster, Frederick L.
AU - Gelman, Benjamin B.
AU - Visvesvara, Govinda S.
N1 - Copyright:
Copyright 2021 Elsevier B.V., All rights reserved.
PY - 2009/4/15
Y1 - 2009/4/15
N2 - Pathogenic free-living amoebae, such as Acanthamoeba species, Balamuthia mandrillaris, and Naegleria fowleri, are known to cause infections of the central nervous system in human and other animals. In 2001, a case of human encephalitis was reported that was caused by another amoeba with morphological features suggestive of Sappinia. The amoeba originally identified as Sappinia diploidea was identified, most likely as S. pedata, by use of newly developed real-time polymerase chain reaction assays. This amoeba had previously been found only in environmental sources, such as soil and tree bark. The results illustrate the potential for other freeliving amoebae, which are not normally associated with human disease, to cause occasional infections.
AB - Pathogenic free-living amoebae, such as Acanthamoeba species, Balamuthia mandrillaris, and Naegleria fowleri, are known to cause infections of the central nervous system in human and other animals. In 2001, a case of human encephalitis was reported that was caused by another amoeba with morphological features suggestive of Sappinia. The amoeba originally identified as Sappinia diploidea was identified, most likely as S. pedata, by use of newly developed real-time polymerase chain reaction assays. This amoeba had previously been found only in environmental sources, such as soil and tree bark. The results illustrate the potential for other freeliving amoebae, which are not normally associated with human disease, to cause occasional infections.
UR - http://www.scopus.com/inward/record.url?scp=65649144191&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=65649144191&partnerID=8YFLogxK
U2 - 10.1086/597473
DO - 10.1086/597473
M3 - Article
C2 - 19302010
AN - SCOPUS:65649144191
SN - 0022-1899
VL - 199
SP - 1139
EP - 1142
JO - Journal of Infectious Diseases
JF - Journal of Infectious Diseases
IS - 8
ER -