Molecular confirmation of sappinia pedata as a causative agent of amoebic encephalitis

Yvonne Qvarnstrom, Alexandre J. Da Silva, Frederick L. Schuster, Benjamin Gelman, Govinda S. Visvesvara

Research output: Contribution to journalArticle

54 Citations (Scopus)

Abstract

Pathogenic free-living amoebae, such as Acanthamoeba species, Balamuthia mandrillaris, and Naegleria fowleri, are known to cause infections of the central nervous system in human and other animals. In 2001, a case of human encephalitis was reported that was caused by another amoeba with morphological features suggestive of Sappinia. The amoeba originally identified as Sappinia diploidea was identified, most likely as S. pedata, by use of newly developed real-time polymerase chain reaction assays. This amoeba had previously been found only in environmental sources, such as soil and tree bark. The results illustrate the potential for other freeliving amoebae, which are not normally associated with human disease, to cause occasional infections.

Original languageEnglish
Pages (from-to)1139-1142
Number of pages4
JournalJournal of Infectious Diseases
Volume199
Issue number8
DOIs
StatePublished - Apr 15 2009

Fingerprint

Amoeba
Encephalitis
Balamuthia mandrillaris
Naegleria fowleri
Plant Bark
Acanthamoeba
Central Nervous System Infections
Real-Time Polymerase Chain Reaction
Soil
Infection

ASJC Scopus subject areas

  • Infectious Diseases
  • Immunology and Allergy

Cite this

Qvarnstrom, Y., Da Silva, A. J., Schuster, F. L., Gelman, B., & Visvesvara, G. S. (2009). Molecular confirmation of sappinia pedata as a causative agent of amoebic encephalitis. Journal of Infectious Diseases, 199(8), 1139-1142. https://doi.org/10.1086/597473

Molecular confirmation of sappinia pedata as a causative agent of amoebic encephalitis. / Qvarnstrom, Yvonne; Da Silva, Alexandre J.; Schuster, Frederick L.; Gelman, Benjamin; Visvesvara, Govinda S.

In: Journal of Infectious Diseases, Vol. 199, No. 8, 15.04.2009, p. 1139-1142.

Research output: Contribution to journalArticle

Qvarnstrom, Y, Da Silva, AJ, Schuster, FL, Gelman, B & Visvesvara, GS 2009, 'Molecular confirmation of sappinia pedata as a causative agent of amoebic encephalitis', Journal of Infectious Diseases, vol. 199, no. 8, pp. 1139-1142. https://doi.org/10.1086/597473
Qvarnstrom Y, Da Silva AJ, Schuster FL, Gelman B, Visvesvara GS. Molecular confirmation of sappinia pedata as a causative agent of amoebic encephalitis. Journal of Infectious Diseases. 2009 Apr 15;199(8):1139-1142. https://doi.org/10.1086/597473
Qvarnstrom, Yvonne ; Da Silva, Alexandre J. ; Schuster, Frederick L. ; Gelman, Benjamin ; Visvesvara, Govinda S. / Molecular confirmation of sappinia pedata as a causative agent of amoebic encephalitis. In: Journal of Infectious Diseases. 2009 ; Vol. 199, No. 8. pp. 1139-1142.
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