TY - JOUR
T1 - Molecular epidemiology of dengue virus type 3 in Northern South America
T2 - 2000-2005
AU - Kochel, Tadeusz
AU - Aguilar, Patricia
AU - Felices, Vidal
AU - Comach, Guillermo
AU - Cruz, Cristopher
AU - Alava, Aracely
AU - Vargas, Jorge
AU - Olson, James
AU - Blair, Patrick
N1 - Funding Information:
We thank Zonia Rios, Roxana Caceda and Carolina Guevara for invaluable technical support. This study was funded by the United States Department of Defense Global Emerging Infections Systems Research Program, WORK UNIT NUMBER: 847705.82000.25GB.B0016. The study protocol was approved by the Naval Medical Research Center Institutional Review Board (Protocols NMRCD.2000.0009 and NMRCD.2000.0006) in compliance with all applicable Federal regulations governing the protection of human subjects.
PY - 2008/9
Y1 - 2008/9
N2 - A phylogenetic approach was used to identify genetic variants of DENV-3 subtype III that may have emerged during or after its expansion throughout South America. We sequenced the capsid, premembrane/membrane and envelope genes from 22 DENV-3 strains isolated from Venezuela, Bolivia, Ecuador and Peru between 2000 and 2005. Phylogenetic analysis showed that the isolates sequenced in this study formed three clades within subtype III: one with the isolates from Venezuela, one with the Bolivian isolates and one with the isolates from Ecuador and Peru.
AB - A phylogenetic approach was used to identify genetic variants of DENV-3 subtype III that may have emerged during or after its expansion throughout South America. We sequenced the capsid, premembrane/membrane and envelope genes from 22 DENV-3 strains isolated from Venezuela, Bolivia, Ecuador and Peru between 2000 and 2005. Phylogenetic analysis showed that the isolates sequenced in this study formed three clades within subtype III: one with the isolates from Venezuela, one with the Bolivian isolates and one with the isolates from Ecuador and Peru.
KW - Dengue-3 evolution
KW - Dengue-3 transmission
KW - Dengue-3 virus
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U2 - 10.1016/j.meegid.2008.06.008
DO - 10.1016/j.meegid.2008.06.008
M3 - Article
C2 - 18674640
AN - SCOPUS:50649113938
VL - 8
SP - 682
EP - 688
JO - Infection, Genetics and Evolution
JF - Infection, Genetics and Evolution
SN - 1567-1348
IS - 5
ER -