Molecular epidemiology of dengue virus type 3 in Northern South America

2000-2005

Tadeusz Kochel, Patricia Aguilar, Vidal Felices, Guillermo Comach, Cristopher Cruz, Aracely Alava, Jorge Vargas, James Olson, Patrick Blair

Research output: Contribution to journalArticle

31 Citations (Scopus)

Abstract

A phylogenetic approach was used to identify genetic variants of DENV-3 subtype III that may have emerged during or after its expansion throughout South America. We sequenced the capsid, premembrane/membrane and envelope genes from 22 DENV-3 strains isolated from Venezuela, Bolivia, Ecuador and Peru between 2000 and 2005. Phylogenetic analysis showed that the isolates sequenced in this study formed three clades within subtype III: one with the isolates from Venezuela, one with the Bolivian isolates and one with the isolates from Ecuador and Peru.

Original languageEnglish (US)
Pages (from-to)682-688
Number of pages7
JournalInfection, Genetics and Evolution
Volume8
Issue number5
DOIs
StatePublished - Sep 2008
Externally publishedYes

Fingerprint

Ecuador
Dengue virus
Venezuela
Dengue Virus
molecular epidemiology
Peru
Molecular Epidemiology
South America
epidemiology
North America
virus
Bolivia
phylogenetics
capsid
Capsid
phylogeny
membrane
Membranes
gene
Genes

Keywords

  • Dengue-3 evolution
  • Dengue-3 transmission
  • Dengue-3 virus

ASJC Scopus subject areas

  • Ecology, Evolution, Behavior and Systematics
  • Genetics
  • Microbiology
  • Infectious Diseases

Cite this

Molecular epidemiology of dengue virus type 3 in Northern South America : 2000-2005. / Kochel, Tadeusz; Aguilar, Patricia; Felices, Vidal; Comach, Guillermo; Cruz, Cristopher; Alava, Aracely; Vargas, Jorge; Olson, James; Blair, Patrick.

In: Infection, Genetics and Evolution, Vol. 8, No. 5, 09.2008, p. 682-688.

Research output: Contribution to journalArticle

Kochel, T, Aguilar, P, Felices, V, Comach, G, Cruz, C, Alava, A, Vargas, J, Olson, J & Blair, P 2008, 'Molecular epidemiology of dengue virus type 3 in Northern South America: 2000-2005', Infection, Genetics and Evolution, vol. 8, no. 5, pp. 682-688. https://doi.org/10.1016/j.meegid.2008.06.008
Kochel, Tadeusz ; Aguilar, Patricia ; Felices, Vidal ; Comach, Guillermo ; Cruz, Cristopher ; Alava, Aracely ; Vargas, Jorge ; Olson, James ; Blair, Patrick. / Molecular epidemiology of dengue virus type 3 in Northern South America : 2000-2005. In: Infection, Genetics and Evolution. 2008 ; Vol. 8, No. 5. pp. 682-688.
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