Molecular epidemiology of dengue virus type 3 in Northern South America: 2000-2005

Tadeusz Kochel, Patricia Aguilar, Vidal Felices, Guillermo Comach, Cristopher Cruz, Aracely Alava, Jorge Vargas, James Olson, Patrick Blair

Research output: Contribution to journalArticle

33 Scopus citations

Abstract

A phylogenetic approach was used to identify genetic variants of DENV-3 subtype III that may have emerged during or after its expansion throughout South America. We sequenced the capsid, premembrane/membrane and envelope genes from 22 DENV-3 strains isolated from Venezuela, Bolivia, Ecuador and Peru between 2000 and 2005. Phylogenetic analysis showed that the isolates sequenced in this study formed three clades within subtype III: one with the isolates from Venezuela, one with the Bolivian isolates and one with the isolates from Ecuador and Peru.

Original languageEnglish (US)
Pages (from-to)682-688
Number of pages7
JournalInfection, Genetics and Evolution
Volume8
Issue number5
DOIs
StatePublished - Sep 1 2008
Externally publishedYes

Keywords

  • Dengue-3 evolution
  • Dengue-3 transmission
  • Dengue-3 virus

ASJC Scopus subject areas

  • Microbiology
  • Ecology, Evolution, Behavior and Systematics
  • Molecular Biology
  • Genetics
  • Microbiology (medical)
  • Infectious Diseases

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    Kochel, T., Aguilar, P., Felices, V., Comach, G., Cruz, C., Alava, A., Vargas, J., Olson, J., & Blair, P. (2008). Molecular epidemiology of dengue virus type 3 in Northern South America: 2000-2005. Infection, Genetics and Evolution, 8(5), 682-688. https://doi.org/10.1016/j.meegid.2008.06.008