Molecular epidemiology of dengue virus type 3 in Northern South America: 2000-2005

Tadeusz Kochel; Patricia Aguilar; Vidal Felices; Guillermo Comach; Cristopher Cruz; Aracely Alava; Jorge Vargas; James Olson; Patrick Blair

doi:10.1016/j.meegid.2008.06.008

Molecular epidemiology of dengue virus type 3 in Northern South America: 2000-2005

Tadeusz Kochel
, Patricia Aguilar
, Vidal Felices
, Guillermo Comach
, Cristopher Cruz
, Aracely Alava
, Jorge Vargas
, James Olson
, Patrick Blair

Research output: Contribution to journal › Article › peer-review

39 Scopus citations

Abstract

A phylogenetic approach was used to identify genetic variants of DENV-3 subtype III that may have emerged during or after its expansion throughout South America. We sequenced the capsid, premembrane/membrane and envelope genes from 22 DENV-3 strains isolated from Venezuela, Bolivia, Ecuador and Peru between 2000 and 2005. Phylogenetic analysis showed that the isolates sequenced in this study formed three clades within subtype III: one with the isolates from Venezuela, one with the Bolivian isolates and one with the isolates from Ecuador and Peru.

Original language	English (US)
Pages (from-to)	682-688
Number of pages	7
Journal	Infection, Genetics and Evolution
Volume	8
Issue number	5
DOIs	https://doi.org/10.1016/j.meegid.2008.06.008
State	Published - Sep 2008
Externally published	Yes

Keywords

Dengue-3 evolution
Dengue-3 transmission
Dengue-3 virus

ASJC Scopus subject areas

Microbiology
Ecology, Evolution, Behavior and Systematics
Molecular Biology
Genetics
Microbiology (medical)
Infectious Diseases

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10.1016/j.meegid.2008.06.008

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@article{a103417b2c0a4c4aa51b47bd40c8a444,

title = "Molecular epidemiology of dengue virus type 3 in Northern South America: 2000-2005",

abstract = "A phylogenetic approach was used to identify genetic variants of DENV-3 subtype III that may have emerged during or after its expansion throughout South America. We sequenced the capsid, premembrane/membrane and envelope genes from 22 DENV-3 strains isolated from Venezuela, Bolivia, Ecuador and Peru between 2000 and 2005. Phylogenetic analysis showed that the isolates sequenced in this study formed three clades within subtype III: one with the isolates from Venezuela, one with the Bolivian isolates and one with the isolates from Ecuador and Peru.",

keywords = "Dengue-3 evolution, Dengue-3 transmission, Dengue-3 virus",

author = "Tadeusz Kochel and Patricia Aguilar and Vidal Felices and Guillermo Comach and Cristopher Cruz and Aracely Alava and Jorge Vargas and James Olson and Patrick Blair",

note = "Funding Information: We thank Zonia Rios, Roxana Caceda and Carolina Guevara for invaluable technical support. This study was funded by the United States Department of Defense Global Emerging Infections Systems Research Program, WORK UNIT NUMBER: 847705.82000.25GB.B0016. The study protocol was approved by the Naval Medical Research Center Institutional Review Board (Protocols NMRCD.2000.0009 and NMRCD.2000.0006) in compliance with all applicable Federal regulations governing the protection of human subjects. ",

year = "2008",

month = sep,

doi = "10.1016/j.meegid.2008.06.008",

language = "English (US)",

volume = "8",

pages = "682--688",

journal = "Infection, Genetics and Evolution",

issn = "1567-1348",

publisher = "Elsevier B.V.",

number = "5",

}

TY - JOUR

T1 - Molecular epidemiology of dengue virus type 3 in Northern South America

T2 - 2000-2005

AU - Kochel, Tadeusz

AU - Aguilar, Patricia

AU - Felices, Vidal

AU - Comach, Guillermo

AU - Cruz, Cristopher

AU - Alava, Aracely

AU - Vargas, Jorge

AU - Olson, James

AU - Blair, Patrick

N1 - Funding Information: We thank Zonia Rios, Roxana Caceda and Carolina Guevara for invaluable technical support. This study was funded by the United States Department of Defense Global Emerging Infections Systems Research Program, WORK UNIT NUMBER: 847705.82000.25GB.B0016. The study protocol was approved by the Naval Medical Research Center Institutional Review Board (Protocols NMRCD.2000.0009 and NMRCD.2000.0006) in compliance with all applicable Federal regulations governing the protection of human subjects.

PY - 2008/9

Y1 - 2008/9

N2 - A phylogenetic approach was used to identify genetic variants of DENV-3 subtype III that may have emerged during or after its expansion throughout South America. We sequenced the capsid, premembrane/membrane and envelope genes from 22 DENV-3 strains isolated from Venezuela, Bolivia, Ecuador and Peru between 2000 and 2005. Phylogenetic analysis showed that the isolates sequenced in this study formed three clades within subtype III: one with the isolates from Venezuela, one with the Bolivian isolates and one with the isolates from Ecuador and Peru.

AB - A phylogenetic approach was used to identify genetic variants of DENV-3 subtype III that may have emerged during or after its expansion throughout South America. We sequenced the capsid, premembrane/membrane and envelope genes from 22 DENV-3 strains isolated from Venezuela, Bolivia, Ecuador and Peru between 2000 and 2005. Phylogenetic analysis showed that the isolates sequenced in this study formed three clades within subtype III: one with the isolates from Venezuela, one with the Bolivian isolates and one with the isolates from Ecuador and Peru.

KW - Dengue-3 evolution

KW - Dengue-3 transmission

KW - Dengue-3 virus

UR - https://www.scopus.com/pages/publications/50649113938

UR - https://www.scopus.com/pages/publications/50649113938#tab=citedBy

U2 - 10.1016/j.meegid.2008.06.008

DO - 10.1016/j.meegid.2008.06.008

M3 - Article

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AN - SCOPUS:50649113938

SN - 1567-1348

VL - 8

SP - 682

EP - 688

JO - Infection, Genetics and Evolution

JF - Infection, Genetics and Evolution

IS - 5

ER -

Molecular epidemiology of dengue virus type 3 in Northern South America: 2000-2005

Abstract

Keywords

ASJC Scopus subject areas

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