TY - JOUR
T1 - Molecular Epidemiology of Western Equine Encephalitis Virus, South America, 2023–2024
AU - Campos, Aline Scarpellini
AU - Franco, Ana Claúdia
AU - Godinho, Fernanda M.
AU - Huff, Rosana
AU - Candido, Darlan S.
AU - da Cruz Cardoso, Jader
AU - Hua, Xinyi
AU - Claro, Ingra M.
AU - Morais, Paola
AU - Franceschina, Carolina
AU - de Lima Bermann, Thales
AU - dos Santos, Franciellen Machado
AU - Bauermann, Milena
AU - Selayaran, Tainá Machado
AU - Ruivo, Amanda Pellenz
AU - Santin, Cristiane
AU - Bonella, Juciane
AU - Rodenbusch, Carla
AU - Ferreira, José Carlos
AU - Weaver, Scott C.
AU - Gewehr, Vilar Ricardo
AU - Wallau, Gabriel Luz
AU - De Souza, William
AU - Salvato, Richard Steiner
N1 - Publisher Copyright:
© 2024 Centers for Disease Control and Prevention (CDC). All rights reserved.
PY - 2024/9/1
Y1 - 2024/9/1
N2 - Western equine encephalitis virus (WEEV) is a mosquitoborne virus that reemerged in December 2023 in Argentina and Uruguay, causing a major outbreak. We investigated the outbreak using epidemiologic, entomological, and genomic analyses, focusing on WEEV circulation near the Argentina‒Uruguay border in Rio Grande do Sul state, Brazil. During November 2023‒April 2024, the outbreak in Argentina and Uruguay resulted in 217 human cases, 12 of which were fatal, and 2,548 equine cases. We determined cases on the basis of laboratory and clinical epidemiologic criteria. We characterized 3 fatal equine cases caused by a novel WEEV lineage identified through a nearly complete coding sequence analysis, which we propose as lineage C. Our findings highlight the importance of continued surveillance and equine vaccination to control future WEEV outbreaks in South America.
AB - Western equine encephalitis virus (WEEV) is a mosquitoborne virus that reemerged in December 2023 in Argentina and Uruguay, causing a major outbreak. We investigated the outbreak using epidemiologic, entomological, and genomic analyses, focusing on WEEV circulation near the Argentina‒Uruguay border in Rio Grande do Sul state, Brazil. During November 2023‒April 2024, the outbreak in Argentina and Uruguay resulted in 217 human cases, 12 of which were fatal, and 2,548 equine cases. We determined cases on the basis of laboratory and clinical epidemiologic criteria. We characterized 3 fatal equine cases caused by a novel WEEV lineage identified through a nearly complete coding sequence analysis, which we propose as lineage C. Our findings highlight the importance of continued surveillance and equine vaccination to control future WEEV outbreaks in South America.
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U2 - 10.3201/eid3009.240530
DO - 10.3201/eid3009.240530
M3 - Article
C2 - 39173662
AN - SCOPUS:85202000300
SN - 1080-6040
VL - 30
SP - 1834
EP - 1840
JO - Emerging infectious diseases
JF - Emerging infectious diseases
IS - 9
ER -