Diseases caused by protozoans and helminthes are some of the most common afflicting humans around the world, and yet they are some of the most scientifically neglected regarding their pathogenesis, diagnosis, and treatment. In this chapter, principles of molecular pathogenesis of the most common protozoan and helminth infections are discussed. Emphasis is placed on immunopathology (innate and adaptive immune responses), parasitic proteases, and immunomodulation by parasites. Selected protozoan and helminth infections are discussed in detail.
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