An essential goal in the treatment of the acute respiratory distress syndrome is the maintenance of adequate oxygenation, but deciding on the most appropriate therapeutic option depends on clinical judgment as to whether intrapulmonary shunting or a combination of shunting and ventilation-perfusion disturbance or mismatch is responsible for impaired pulmonary gas exchange and resultant hypoxemia. Because the physical findings of hypoxemia are nonspecific, the clinician may not be able to adequately assess the severity of oxygen depletion without measuring PaO2. However, the changes in lung function that cause hypoxemia cannot be inferred from measurements of PaO2. Therefore, several oxygenation indices have been developed to guide the assessment of the cause of hypoxemia and the selection of a management strategy.
|Number of pages
|Journal of Critical Illness
|Published - Jan 1 2001
ASJC Scopus subject areas
- Critical Care and Intensive Care Medicine