Morphological and functional MR imaging of Lhermitte-Duclos disease with pathology correlate

A. Cianfoni; M. Wintermark; F. Piludu; Q. G. D'Alessandris; L. Lauriola; M. Visocchi; C. Colosimo

doi:10.1016/j.neurad.2008.05.002

Morphological and functional MR imaging of Lhermitte-Duclos disease with pathology correlate

A. Cianfoni
, M. Wintermark
, F. Piludu
, Q. G. D'Alessandris
, L. Lauriola
, M. Visocchi
, C. Colosimo

Research output: Contribution to journal › Article › peer-review

20 Scopus citations

Abstract

Lhermitte-Duclos disease (LDD) is a rare benign lesion of uncertain pathogenesis characterised by distortion of the normal cerebellar laminar cytoarchitecture. We report a case of LDD thoroughly characterized by advanced magnetic resonance imaging techniques, with diffusion-weighted, perfusion-weighted and post-gadolinium sequences. Imaging showed restricted diffusion consistent with high cellularity, high degree of vascularity and preserved blood-brain barrier permeability, correlating with pathology.

Original language	English (US)
Pages (from-to)	297-300
Number of pages	4
Journal	Journal of Neuroradiology
Volume	35
Issue number	5
DOIs	https://doi.org/10.1016/j.neurad.2008.05.002
State	Published - Dec 2008
Externally published	Yes

Keywords

Diffusion-weighted imaging
Gadolinium
Lhermitte-Duclos disease
MRI
Perfusion

ASJC Scopus subject areas

Radiological and Ultrasound Technology
Radiology Nuclear Medicine and imaging
Clinical Neurology

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10.1016/j.neurad.2008.05.002

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title = "Morphological and functional MR imaging of Lhermitte-Duclos disease with pathology correlate",

abstract = "Lhermitte-Duclos disease (LDD) is a rare benign lesion of uncertain pathogenesis characterised by distortion of the normal cerebellar laminar cytoarchitecture. We report a case of LDD thoroughly characterized by advanced magnetic resonance imaging techniques, with diffusion-weighted, perfusion-weighted and post-gadolinium sequences. Imaging showed restricted diffusion consistent with high cellularity, high degree of vascularity and preserved blood-brain barrier permeability, correlating with pathology.",

keywords = "Diffusion-weighted imaging, Gadolinium, Lhermitte-Duclos disease, MRI, Perfusion",

author = "A. Cianfoni and M. Wintermark and F. Piludu and D'Alessandris, \{Q. G.\} and L. Lauriola and M. Visocchi and C. Colosimo",

year = "2008",

month = dec,

doi = "10.1016/j.neurad.2008.05.002",

language = "English (US)",

volume = "35",

pages = "297--300",

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T1 - Morphological and functional MR imaging of Lhermitte-Duclos disease with pathology correlate

AU - Cianfoni, A.

AU - Wintermark, M.

AU - Piludu, F.

AU - D'Alessandris, Q. G.

AU - Lauriola, L.

AU - Visocchi, M.

AU - Colosimo, C.

PY - 2008/12

Y1 - 2008/12

N2 - Lhermitte-Duclos disease (LDD) is a rare benign lesion of uncertain pathogenesis characterised by distortion of the normal cerebellar laminar cytoarchitecture. We report a case of LDD thoroughly characterized by advanced magnetic resonance imaging techniques, with diffusion-weighted, perfusion-weighted and post-gadolinium sequences. Imaging showed restricted diffusion consistent with high cellularity, high degree of vascularity and preserved blood-brain barrier permeability, correlating with pathology.

AB - Lhermitte-Duclos disease (LDD) is a rare benign lesion of uncertain pathogenesis characterised by distortion of the normal cerebellar laminar cytoarchitecture. We report a case of LDD thoroughly characterized by advanced magnetic resonance imaging techniques, with diffusion-weighted, perfusion-weighted and post-gadolinium sequences. Imaging showed restricted diffusion consistent with high cellularity, high degree of vascularity and preserved blood-brain barrier permeability, correlating with pathology.

KW - Diffusion-weighted imaging

KW - Gadolinium

KW - Lhermitte-Duclos disease

KW - MRI

KW - Perfusion

UR - https://www.scopus.com/pages/publications/57049163009

UR - https://www.scopus.com/pages/publications/57049163009#tab=citedBy

U2 - 10.1016/j.neurad.2008.05.002

DO - 10.1016/j.neurad.2008.05.002

M3 - Article

C2 - 18692898

AN - SCOPUS:57049163009

SN - 0150-9861

VL - 35

SP - 297

EP - 300

JO - Journal of Neuroradiology

JF - Journal of Neuroradiology

IS - 5

ER -

Morphological and functional MR imaging of Lhermitte-Duclos disease with pathology correlate

Abstract

Keywords

ASJC Scopus subject areas

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