Morphology and morphogenesis of arenaviruses

F. A. Murphy, S. G. Whitfield

Research output: Contribution to journalArticle

33 Citations (Scopus)

Abstract

Arenaviruses have unique structural characteristics; they are pleomorphic, have a mean diameter of 110-130 nm, and consist of a membranous envelope with surface projections surrounding an interior containing ribosomes and filaments. Virus particles bud from plasma membranes of infected cells and in many cases large intracytoplasmic inclusion bodies are formed. These characteristics allow generic identification, but no differentiation of individual viruses. Ultrastructural identification of virus particles and pathologic processes in infected tissues of man and experimental animals is important in understanding the nature of arenaviral pathogenesis. Such identification also contributes to the understanding of the mechanisms of viral shedding and transmission in reservoir host species.

Original languageEnglish (US)
Pages (from-to)409-419
Number of pages11
JournalBulletin of the World Health Organization
Volume52
Issue number4-5 6
StatePublished - 1975

Fingerprint

Arenavirus
Morphogenesis
Virion
Virus Shedding
Inclusion Bodies
Pathologic Processes
Ribosomes
Cell Membrane
Viruses

ASJC Scopus subject areas

  • Public Health, Environmental and Occupational Health

Cite this

Murphy, F. A., & Whitfield, S. G. (1975). Morphology and morphogenesis of arenaviruses. Bulletin of the World Health Organization, 52(4-5 6), 409-419.

Morphology and morphogenesis of arenaviruses. / Murphy, F. A.; Whitfield, S. G.

In: Bulletin of the World Health Organization, Vol. 52, No. 4-5 6, 1975, p. 409-419.

Research output: Contribution to journalArticle

Murphy, FA & Whitfield, SG 1975, 'Morphology and morphogenesis of arenaviruses', Bulletin of the World Health Organization, vol. 52, no. 4-5 6, pp. 409-419.
Murphy, F. A. ; Whitfield, S. G. / Morphology and morphogenesis of arenaviruses. In: Bulletin of the World Health Organization. 1975 ; Vol. 52, No. 4-5 6. pp. 409-419.
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