Mouse models for cancer research

Wei Zhang, Lynette Moore, Ping Ji

Research output: Contribution to journalArticle

9 Scopus citations

Abstract

Mouse models of cancer enable researchers to learn about tumor biology in complicated and dynamic physiological systems. Since the development of gene targeting in mice, cancer biologists have been among the most frequent users of transgenic mouse models, which have dramatically increased knowledge about how cancers form and grow. The Chinese Journal of Cancer will publish a series of papers reporting the use of mouse models in studying genetic events in cancer cases. This editorial is an overview of the development and applications of mouse models of cancer and directs the reader to upcoming papers describing the use of these models to be published in coming issues, beginning with three articles in the current issue.

Original languageEnglish (US)
Pages (from-to)149-152
Number of pages4
JournalChinese Journal of Cancer
Volume30
Issue number3
DOIs
StatePublished - 2011

Keywords

  • Gene targeting
  • Knockout mouse
  • Oncogene
  • Stem cells
  • Tumor suppressor gene

ASJC Scopus subject areas

  • Oncology

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