Mucosal bromodomain-containing protein 4 mediates aeroallergen-induced inflammation and remodeling

Keyphrases

• Inflammation 100%
• Bromodomain-containing Protein 4 (BRD4) 100%
• Aeroallergens 100%
• Cat Dander 100%
• Allergic Asthma 60%
• Myofibroblast 60%
• Nuclear factor-B 60%
• Airway Remodeling 60%
• Quantitative RT-PCR 40%
• Histone Acetyltransferase Activity 40%
• Histology 20%
• Mouse Model 20%
• Airway 20%
• Epithelial Cells 20%
• Small Molecules 20%
• Fibrosis 20%
• Allergen 20%
• RelA 20%
• Airway Inflammation 20%
• Pulmonary Function 20%
• Polymerase II 20%
• Immunofluorescence 20%
• Innate Inflammation 20%
• In Situ 20%
• Subepithelial Myofibroblasts 20%
• Mucosal Inflammation 20%
• Biopsy Specimen 20%
• State Change 20%
• Human Small Airway Epithelial Cells 20%
• Cell State 20%
• Mesenchymal Transition 20%
• Selected Reaction Monitoring 20%
• Epithelial-mesenchymal Transition 20%
• Collagen Content 20%
• Extracellular Matrix Deposition 20%
• Leukocyte Recruitment 20%
• Chromatin Landscape 20%
• Frequent Exacerbator 20%
• B Signaling Pathway 20%
• Fibrogenic 20%
• Bronchial Biopsy 20%
• Experimental Asthma 20%
• Pro-fibrogenic 20%
• Asthma Risk 20%
• Proximity Ligation Assay 20%
• BRD4 Inhibitor 20%
• IgE Sensitization 20%
• Therapeutic Modulation 20%
• Matrix Expansion 20%

Biochemistry, Genetics and Molecular Biology

• Bromodomain 100%
• BRD4 100%
• Dander 100%
• Myofibroblast 80%
• Complement Factor B 60%
• Quantitative Reverse Transcription Polymerase Chain Reaction 40%
• Histone Acetyltransferase 40%
• Mouse Model 20%
• Leukocyte 20%
• Signal Transduction 20%
• Lung Function 20%
• Small Molecule 20%
• Immunoglobulin E 20%
• Polymerase 20%
• Immunofluorescence 20%
• Sensitization 20%
• Mesenchymal-Epithelial Transition 20%
• Selected Reaction Monitoring 20%
• Fibrogenesis 20%
• Carisoprodol 20%

Immunology and Microbiology

• Dander 100%
• Myofibroblast 80%
• Complement Factor B 60%
• Allergic Asthma 60%
• Quantitative Reverse Transcription Polymerase Chain Reaction 40%
• Signal Transduction 20%
• Mouse Model 20%
• Sensitization 20%
• Allergen 20%
• Asthma 20%
• Immunoglobulin E 20%
• Lung Function 20%
• Extracellular Matrix 20%
• Immunofluorescence 20%
• Epithelial Mesenchymal Transition 20%
• Leukocyte Recruitment 20%
• Fibrogenesis 20%
• Experimental Asthma 20%
• Proximity Ligation Assay 20%