Multiphoton autofluorescence microscopy and second harmonic generation microscopy of oral epithelial neoplasms

Gracie Vargas; Tuya Shilagard; Ki Hong Ho; Susan McCammon

doi:10.1109/IEMBS.2009.5332783

Multiphoton autofluorescence microscopy and second harmonic generation microscopy of oral epithelial neoplasms

Gracie Vargas, Tuya Shilagard, Ki Hong Ho, Susan McCammon

Otolaryngology

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

10 Scopus citations

Abstract

The objective of this study was to evaluate the nonlinear optical microscopy techniques of multiphoton autofluorescence microscopy (MPAM) and second harmonic generation microscopy (SHGM) for noninvasive imaging of oral epithelial carcinogenesis. In vivo imaging was performed in a hamster model for oral carcinogenesis to characterize optical and morphometric alterations during neoplastic transformation. Data is presented showing alterations in morphometry and collagen density during the precancerous phase of neoplastic transformation.

Original language	English (US)
Title of host publication	Proceedings of the 31st Annual International Conference of the IEEE Engineering in Medicine and Biology Society
Subtitle of host publication	Engineering the Future of Biomedicine, EMBC 2009
Publisher	IEEE Computer Society
Pages	6311-6313
Number of pages	3
ISBN (Print)	9781424432967
DOIs	https://doi.org/10.1109/IEMBS.2009.5332783
State	Published - 2009
Event	31st Annual International Conference of the IEEE Engineering in Medicine and Biology Society: Engineering the Future of Biomedicine, EMBC 2009 - Minneapolis, MN, United States Duration: Sep 2 2009 → Sep 6 2009

Publication series

Name	Proceedings of the 31st Annual International Conference of the IEEE Engineering in Medicine and Biology Society: Engineering the Future of Biomedicine, EMBC 2009

Other

Other	31st Annual International Conference of the IEEE Engineering in Medicine and Biology Society: Engineering the Future of Biomedicine, EMBC 2009
Country	United States
City	Minneapolis, MN
Period	9/2/09 → 9/6/09

ASJC Scopus subject areas

Cell Biology
Developmental Biology
Biomedical Engineering
Medicine(all)

Access to Document

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Cite this

Vargas, G., Shilagard, T., Ho, K. H., & McCammon, S. (2009). Multiphoton autofluorescence microscopy and second harmonic generation microscopy of oral epithelial neoplasms. In Proceedings of the 31st Annual International Conference of the IEEE Engineering in Medicine and Biology Society: Engineering the Future of Biomedicine, EMBC 2009 (pp. 6311-6313). [5332783] (Proceedings of the 31st Annual International Conference of the IEEE Engineering in Medicine and Biology Society: Engineering the Future of Biomedicine, EMBC 2009). IEEE Computer Society. https://doi.org/10.1109/IEMBS.2009.5332783

Multiphoton autofluorescence microscopy and second harmonic generation microscopy of oral epithelial neoplasms. / Vargas, Gracie; Shilagard, Tuya; Ho, Ki Hong; McCammon, Susan.

Proceedings of the 31st Annual International Conference of the IEEE Engineering in Medicine and Biology Society: Engineering the Future of Biomedicine, EMBC 2009. IEEE Computer Society, 2009. p. 6311-6313 5332783 (Proceedings of the 31st Annual International Conference of the IEEE Engineering in Medicine and Biology Society: Engineering the Future of Biomedicine, EMBC 2009).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Vargas, G, Shilagard, T, Ho, KH & McCammon, S 2009, Multiphoton autofluorescence microscopy and second harmonic generation microscopy of oral epithelial neoplasms. in Proceedings of the 31st Annual International Conference of the IEEE Engineering in Medicine and Biology Society: Engineering the Future of Biomedicine, EMBC 2009., 5332783, Proceedings of the 31st Annual International Conference of the IEEE Engineering in Medicine and Biology Society: Engineering the Future of Biomedicine, EMBC 2009, IEEE Computer Society, pp. 6311-6313, 31st Annual International Conference of the IEEE Engineering in Medicine and Biology Society: Engineering the Future of Biomedicine, EMBC 2009, Minneapolis, MN, United States, 9/2/09. https://doi.org/10.1109/IEMBS.2009.5332783

Vargas G, Shilagard T, Ho KH, McCammon S. Multiphoton autofluorescence microscopy and second harmonic generation microscopy of oral epithelial neoplasms. In Proceedings of the 31st Annual International Conference of the IEEE Engineering in Medicine and Biology Society: Engineering the Future of Biomedicine, EMBC 2009. IEEE Computer Society. 2009. p. 6311-6313. 5332783. (Proceedings of the 31st Annual International Conference of the IEEE Engineering in Medicine and Biology Society: Engineering the Future of Biomedicine, EMBC 2009). https://doi.org/10.1109/IEMBS.2009.5332783

Vargas, Gracie ; Shilagard, Tuya ; Ho, Ki Hong ; McCammon, Susan. / Multiphoton autofluorescence microscopy and second harmonic generation microscopy of oral epithelial neoplasms. Proceedings of the 31st Annual International Conference of the IEEE Engineering in Medicine and Biology Society: Engineering the Future of Biomedicine, EMBC 2009. IEEE Computer Society, 2009. pp. 6311-6313 (Proceedings of the 31st Annual International Conference of the IEEE Engineering in Medicine and Biology Society: Engineering the Future of Biomedicine, EMBC 2009).

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