Abstract
The objective of this study was to evaluate the nonlinear optical microscopy techniques of multiphoton autofluorescence microscopy (MPAM) and second harmonic generation microscopy (SHGM) for noninvasive imaging of oral epithelial carcinogenesis. In vivo imaging was performed in a hamster model for oral carcinogenesis to characterize optical and morphometric alterations during neoplastic transformation. Data is presented showing alterations in morphometry and collagen density during the precancerous phase of neoplastic transformation.
| Original language | English (US) |
|---|---|
| Title of host publication | Proceedings of the 31st Annual International Conference of the IEEE Engineering in Medicine and Biology Society: Engineering the Future of Biomedicine, EMBC 2009 |
| Pages | 6311-6313 |
| Number of pages | 3 |
| DOIs | |
| State | Published - 2009 |
| Externally published | Yes |
| Event | 31st Annual International Conference of the IEEE Engineering in Medicine and Biology Society: Engineering the Future of Biomedicine, EMBC 2009 - Minneapolis, MN, United States Duration: Sep 2 2009 → Sep 6 2009 |
Other
| Other | 31st Annual International Conference of the IEEE Engineering in Medicine and Biology Society: Engineering the Future of Biomedicine, EMBC 2009 |
|---|---|
| Country | United States |
| City | Minneapolis, MN |
| Period | 9/2/09 → 9/6/09 |
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ASJC Scopus subject areas
- Cell Biology
- Developmental Biology
- Biomedical Engineering
- Medicine(all)
Cite this
Multiphoton autofluorescence microscopy and second harmonic generation microscopy of oral epithelial neoplasms. / Vargas, Gracie; Shilagard, Tuya; Ho, Ki Hong; McCammon, Susan.
Proceedings of the 31st Annual International Conference of the IEEE Engineering in Medicine and Biology Society: Engineering the Future of Biomedicine, EMBC 2009. 2009. p. 6311-6313 5332783.Research output: Chapter in Book/Report/Conference proceeding › Conference contribution
}
TY - GEN
T1 - Multiphoton autofluorescence microscopy and second harmonic generation microscopy of oral epithelial neoplasms
AU - Vargas, Gracie
AU - Shilagard, Tuya
AU - Ho, Ki Hong
AU - McCammon, Susan
PY - 2009
Y1 - 2009
N2 - The objective of this study was to evaluate the nonlinear optical microscopy techniques of multiphoton autofluorescence microscopy (MPAM) and second harmonic generation microscopy (SHGM) for noninvasive imaging of oral epithelial carcinogenesis. In vivo imaging was performed in a hamster model for oral carcinogenesis to characterize optical and morphometric alterations during neoplastic transformation. Data is presented showing alterations in morphometry and collagen density during the precancerous phase of neoplastic transformation.
AB - The objective of this study was to evaluate the nonlinear optical microscopy techniques of multiphoton autofluorescence microscopy (MPAM) and second harmonic generation microscopy (SHGM) for noninvasive imaging of oral epithelial carcinogenesis. In vivo imaging was performed in a hamster model for oral carcinogenesis to characterize optical and morphometric alterations during neoplastic transformation. Data is presented showing alterations in morphometry and collagen density during the precancerous phase of neoplastic transformation.
UR - http://www.scopus.com/inward/record.url?scp=77950972509&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=77950972509&partnerID=8YFLogxK
U2 - 10.1109/IEMBS.2009.5332783
DO - 10.1109/IEMBS.2009.5332783
M3 - Conference contribution
SN - 9781424432967
SP - 6311
EP - 6313
BT - Proceedings of the 31st Annual International Conference of the IEEE Engineering in Medicine and Biology Society: Engineering the Future of Biomedicine, EMBC 2009
ER -