Multiphoton autofluorescence microscopy and second harmonic generation microscopy of oral epithelial neoplasms.

Gracie Vargas, Tuya Shilagard, Ki Hong Ho, Susan McCammon

Research output: Contribution to journalArticle

Abstract

The objective of this study was to evaluate the nonlinear optical microscopy techniques of multiphoton autofluorescence microscopy (MPAM) and second harmonic generation microscopy (SHGM) for noninvasive imaging of oral epithelial carcinogenesis. In vivo imaging was performed in a hamster model for oral carcinogenesis to characterize optical and morphometric alterations during neoplastic transformation. Data is presented showing alterations in morphometry and collagen density during the precancerous phase of neoplastic transformation.

Fingerprint

Glandular and Epithelial Neoplasms
Mouth Neoplasms
Harmonic generation
Microscopy
Microscopic examination
Imaging techniques
Carcinogenesis
Collagen
Optical microscopy
Cricetinae

ASJC Scopus subject areas

  • Computer Vision and Pattern Recognition
  • Signal Processing
  • Biomedical Engineering
  • Health Informatics

Cite this

@article{4a9dca5808484a48b0e3af9e11e7832a,
title = "Multiphoton autofluorescence microscopy and second harmonic generation microscopy of oral epithelial neoplasms.",
abstract = "The objective of this study was to evaluate the nonlinear optical microscopy techniques of multiphoton autofluorescence microscopy (MPAM) and second harmonic generation microscopy (SHGM) for noninvasive imaging of oral epithelial carcinogenesis. In vivo imaging was performed in a hamster model for oral carcinogenesis to characterize optical and morphometric alterations during neoplastic transformation. Data is presented showing alterations in morphometry and collagen density during the precancerous phase of neoplastic transformation.",
author = "Gracie Vargas and Tuya Shilagard and Ho, {Ki Hong} and Susan McCammon",
year = "2009",
language = "English (US)",
pages = "6311--6313",
journal = "Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference",
issn = "1557-170X",
publisher = "Institute of Electrical and Electronics Engineers Inc.",

}

TY - JOUR

T1 - Multiphoton autofluorescence microscopy and second harmonic generation microscopy of oral epithelial neoplasms.

AU - Vargas, Gracie

AU - Shilagard, Tuya

AU - Ho, Ki Hong

AU - McCammon, Susan

PY - 2009

Y1 - 2009

N2 - The objective of this study was to evaluate the nonlinear optical microscopy techniques of multiphoton autofluorescence microscopy (MPAM) and second harmonic generation microscopy (SHGM) for noninvasive imaging of oral epithelial carcinogenesis. In vivo imaging was performed in a hamster model for oral carcinogenesis to characterize optical and morphometric alterations during neoplastic transformation. Data is presented showing alterations in morphometry and collagen density during the precancerous phase of neoplastic transformation.

AB - The objective of this study was to evaluate the nonlinear optical microscopy techniques of multiphoton autofluorescence microscopy (MPAM) and second harmonic generation microscopy (SHGM) for noninvasive imaging of oral epithelial carcinogenesis. In vivo imaging was performed in a hamster model for oral carcinogenesis to characterize optical and morphometric alterations during neoplastic transformation. Data is presented showing alterations in morphometry and collagen density during the precancerous phase of neoplastic transformation.

UR - http://www.scopus.com/inward/record.url?scp=84903871322&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84903871322&partnerID=8YFLogxK

M3 - Article

SP - 6311

EP - 6313

JO - Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference

JF - Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference

SN - 1557-170X

ER -