@inproceedings{bc7032bf53cf4a97bf64ab1659c465c1,
title = "Multiscale biomechanical modeling of the human eye",
abstract = "A multiscale modeling approach is presented for advancing understanding of the biomechanical behavior of the human eye under various physiological conditions. The approach involves the development of large and small scale numerical models to predict stress and strain throughout the eye and its constituent anatomical structures that span length scales ranging from centimeters to microns. The numerical models are based on computational fluid dynamic (CFD) analysis combined with a fully-coupled fluid-structure interaction (FSI) capability as well finite element-based structural analysis. Preliminary modeling results of pressure-induced tissue deformation are demonstrated via application to an idealized eye geometry. A physical cadaveric eye model that will be used for model validation is also presented. A discussion is given of challenges and opportunities of using this approach to advance understanding of biomechanical behavior of the human eye.",
keywords = "Eye biomechanics, ICP, IOP, Intracranial fluid structure interactions, Intracranial pressure, Intraocular pressure, ONSD, Optic nerve sheath diameter, Optic nerve stress, Stress and strain of eye tissue",
author = "Karampelas, {Ioannis H.} and Furlani, {Edward P.} and Anthony Nunez and Gianmarco Vizzeri",
year = "2013",
language = "English (US)",
isbn = "9781482205848",
series = "Technical Proceedings of the 2013 NSTI Nanotechnology Conference and Expo, NSTI-Nanotech 2013",
pages = "354--357",
booktitle = "Technical Proceedings of the 2013 NSTI Nanotechnology Conference and Expo, NSTI-Nanotech 2013",
note = "Nanotechnology 2013: Electronics, Devices, Fabrication, MEMS, Fluidics and Computational - 2013 NSTI Nanotechnology Conference and Expo, NSTI-Nanotech 2013 ; Conference date: 12-05-2013 Through 16-05-2013",
}