Multiwavelength optoacoustic system for noninvasive monitoring of cerebral venous oxygenation: A pilot clinical test in the internal jugular vein

Yuriy Y. Petrov, Irina Y. Petrova, Igor A. Patrikeev, Rinat Esenaliev, Donald Prough

Research output: Contribution to journalArticle

74 Citations (Scopus)

Abstract

A noninvasive, high-resolution optoacoustic technique is a promising alternative to currently used invasive methods of brain oxygenation monitoring. We present the results of our pilot clinical test of this technique in healthy volunteers. Multiwavelength optoacoustic measurements (with nanosecond optical parametric oscillator as a source of radiation) were performed on the area of the neck overlying the internal jugular vein, a deeply located large vein that drains blood from the brain and from extracranial tissues. Optoacoustic signals induced in venous blood were measured with high resolution and signal-to-noise ratio despite the presence of a thick layer of overlying tissue (up to 10 mm). The characteristic parameters of the signal at different wavelengths correlated well with the spectrum of the effective attenuation coefficient of blood.

Original languageEnglish (US)
Pages (from-to)1827-1829
Number of pages3
JournalOptics Letters
Volume31
Issue number12
DOIs
StatePublished - Jun 15 2006

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oxygenation
veins
blood
brain
high resolution
attenuation coefficients
parametric amplifiers
signal to noise ratios
radiation
wavelengths

ASJC Scopus subject areas

  • Atomic and Molecular Physics, and Optics

Cite this

Multiwavelength optoacoustic system for noninvasive monitoring of cerebral venous oxygenation : A pilot clinical test in the internal jugular vein. / Petrov, Yuriy Y.; Petrova, Irina Y.; Patrikeev, Igor A.; Esenaliev, Rinat; Prough, Donald.

In: Optics Letters, Vol. 31, No. 12, 15.06.2006, p. 1827-1829.

Research output: Contribution to journalArticle

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