TY - JOUR
T1 - Murine typhus
T2 - A life-threatening presentation of a case in galveston, texas
AU - Perez, Christopher
AU - Hamouda, Diaa
AU - Karnath, Bernard
N1 - Publisher Copyright:
© Am J Case Rep, 2018;.
PY - 2018
Y1 - 2018
N2 - Objective: Background: Case Report: Conclusions: Rare disease Murine typhus is a rare bacterial infection caused by Rickettsia typhi, which is transmitted from rodents to humans through the infected Xenopsylla cheopis flea. The disease presentation is often non-specific, leading to unnecessary tests, and a delay in diagnosis and treatment. A report is presented of a 22-year-old, previously healthy man, who presented with several symptoms and signs that increased in severity, requiring admission to the medical intensive care unit (MICU). After an extensive bacterial and viral laboratory workup, IgM and IgG titers confirmed the diagnosis of murine typhus due to infection by Rickettsia typhi. The patient was treated with doxycycline, which resulted in significant clinical improvement. Murine typhus can present with a characteristic triad of fever, headache, and rash but also with other symptoms and signs and can vary in severity. Given its increasing prevalence in coastal cities, awareness of this infection and early diagnosis and treatment with doxycycline can reduce patient morbidity.
AB - Objective: Background: Case Report: Conclusions: Rare disease Murine typhus is a rare bacterial infection caused by Rickettsia typhi, which is transmitted from rodents to humans through the infected Xenopsylla cheopis flea. The disease presentation is often non-specific, leading to unnecessary tests, and a delay in diagnosis and treatment. A report is presented of a 22-year-old, previously healthy man, who presented with several symptoms and signs that increased in severity, requiring admission to the medical intensive care unit (MICU). After an extensive bacterial and viral laboratory workup, IgM and IgG titers confirmed the diagnosis of murine typhus due to infection by Rickettsia typhi. The patient was treated with doxycycline, which resulted in significant clinical improvement. Murine typhus can present with a characteristic triad of fever, headache, and rash but also with other symptoms and signs and can vary in severity. Given its increasing prevalence in coastal cities, awareness of this infection and early diagnosis and treatment with doxycycline can reduce patient morbidity.
KW - Bacterial Infections
KW - Doxycycline
KW - Rickettsia typhi
KW - Xenopsylla
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U2 - 10.12659/AJCR.909369
DO - 10.12659/AJCR.909369
M3 - Article
C2 - 30559335
AN - SCOPUS:85058764212
SN - 1941-5923
VL - 19
SP - 1503
EP - 1506
JO - American Journal of Case Reports
JF - American Journal of Case Reports
ER -