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Keyphrases
Cancer Stem Cells
100%
MG-63 Cells
100%
Dedifferentiation
100%
Human Osteosarcoma
100%
Mutant p53 Gain of Function
100%
P72R
80%
Gain-of-function
60%
Stemness
60%
Tumor Protein p53 (TP53)
40%
Invasiveness
40%
Osteosarcoma
40%
TP53 Gene
40%
Mutant p53 Protein
40%
Patient Survival
20%
DNA Sequencing
20%
Knockdown
20%
Apoptosis Inhibition
20%
Quantitative PCR
20%
Tumor
20%
Small Interfering RNA (siRNA)
20%
Malignancy
20%
Growth Rate
20%
Western Blot Analysis
20%
P53 Expression
20%
In Cancer
20%
Aggressive Tumor
20%
Ectopic Expression
20%
Tumor Suppressor Gene
20%
New Targets
20%
Multi-copy
20%
Metastatic Tumor
20%
Nuclear Localization
20%
Fluorescence in Situ Hybridization
20%
Quantitative Methylation-specific PCR (Q-MSP)
20%
Stem Cell Lines
20%
Highly Aggressive
20%
Invasive Ability
20%
Cell Cycle Inhibitors
20%
Proliferation Rate
20%
Cancer Stem-like
20%
Immunofluorescence Analysis
20%
Replication Rate
20%
Hypermethylated
20%
Clonogenic Activity
20%
Migration Ability
20%
Protein p53
20%
TRAIL-induced Apoptosis
20%
Multiple mutants
20%
Sphere Formation
20%
Second-line Chemotherapy
20%
Biochemistry, Genetics and Molecular Biology
P53
100%
Cancer Stem Cell
100%
Cell Dedifferentiation
100%
Programmed Cell Death
25%
Cell Cycle
12%
Upregulation
12%
Methylation
12%
DNA Sequence
12%
Immunofluorescence
12%
Ectopic Expression
12%
Reverse Transcription Polymerase Chain Reaction
12%
Tumor Suppressor Gene
12%
Western Blot
12%
Stem Cell Line
12%
Fluorescence in Situ Hybridization
12%
TRAIL
12%
Small Interfering RNA
12%