Mutation in a 17D-204 vaccine substrain-specific envelope protein epitope alters the pathogenesis of yellow fever virus in mice

Keyphrases

• Yellow Fever 100%
• Envelope Protein 100%
• Substrain 100%
• Protein Epitopes 100%
• Neurovirulence 66%
• Epitope 66%
• Virus 33%
• Flavivirus 33%
• Attenuation 33%
• Mouse Model 33%
• Avirulent 33%
• Vaccine Virus 33%
• Conformational Change 33%
• Virus Variants 33%
• Envelope (E) Protein 33%
• E Protein 33%
• Virus Pathogenesis 33%
• Virus Population 33%
• Molecular Determinants 33%
• Mutant Virus 33%
• Adult Mice 33%
• Virus Sequence 33%
• Single Amino Acid Substitution 33%
• Enhanced Virulence 33%
• Resistant Variants 33%
• Avirulence 33%

Immunology and Microbiology

• Epitope 100%
• Yellow Fever Virus 100%
• Neutralization 50%
• Flavivirus 25%
• Mouse Model 25%
• Yellow Fever 25%
• Virus Vaccine 25%
• Revertant 25%
• Conformational Transition 25%
• Virulence 25%