Mycobacterium kansasii osteomyelitis presenting as a solitary lytic lesion of the ulna

Fine-needle aspiration findings and morphologic comparison with other mycobacteria

Vicki J. Schnadig, S. Fiaz Quadri, Fatih Boyvat, Michael Borucki

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

A 35-yr-old woman, with acquired immunodeficiency syndrome, presented with right arm pain, erythema, and swelling. A lyric lesion of the ulna was found by radiograph. Ultrasonic and fluoroscopic guided fine-needle aspiration (FNA) yielded a neutrophilic and histiocytic exudate admixed with abundant long, bacillary forms that appeared as negative images on Papanicolaou stain and as very coarsely beaded acid-fast bacilli, resembling candy canes, on Kinyoun stain. These morphologic features permitted a preliminary diagnosis of mycobacteriosis, possibly of M. kansasii (MK) etiology. Appropriate therapy was initiated and resulted in not only marked symptomatic improvement of osteomyelitis and cellulitis, but resolution of chronic pulmonary infiltrates, presumed to be caused by fibrosis. Culture confirmed MK infection 3 wk after FNA. MK is one of the few mycobacteria that has a sufficiently, characteristic morphology to permit presumptive diagnosis by smear. Culture, however, still remains the definitive method of speciation.

Original languageEnglish (US)
Pages (from-to)94-97
Number of pages4
JournalDiagnostic Cytopathology
Volume19
Issue number2
DOIs
StatePublished - Aug 1998

Fingerprint

Mycobacterium kansasii
Ulna
Osteomyelitis
Mycobacterium
Fine Needle Biopsy
Coloring Agents
Candy
Canes
Mycobacterium Infections
Cellulitis
Exudates and Transudates
Erythema
Ultrasonics
Bacillus
Acquired Immunodeficiency Syndrome
Fibrosis
Pain
Lung
Acids
Therapeutics

Keywords

  • Acquired immune deficiency syndrome
  • Mycobacterium kansasii
  • Osteomyelitis

ASJC Scopus subject areas

  • Anatomy

Cite this

Mycobacterium kansasii osteomyelitis presenting as a solitary lytic lesion of the ulna : Fine-needle aspiration findings and morphologic comparison with other mycobacteria. / Schnadig, Vicki J.; Quadri, S. Fiaz; Boyvat, Fatih; Borucki, Michael.

In: Diagnostic Cytopathology, Vol. 19, No. 2, 08.1998, p. 94-97.

Research output: Contribution to journalArticle

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