Myocardial injury in patients with intracerebral hemorrhage treated with recombinant factor VIIa

R. M. Sugg; N. R. Gonzales; D. E. Matherne; M. Ribo; H. M. Shaltoni; S. Baraniuk; E. A. Noser; J. C. Grotta

doi:10.1212/01.wnl.0000239154.51331.c4

Myocardial injury in patients with intracerebral hemorrhage treated with recombinant factor VIIa

R. M. Sugg
, N. R. Gonzales
, D. E. Matherne
, M. Ribo
, H. M. Shaltoni
, S. Baraniuk
, E. A. Noser
, J. C. Grotta

Research output: Contribution to journal › Article › peer-review

29 Scopus citations

Abstract

We report myocardial injury in 20 recombinant factor VIIa (rFVIIa) treated and 110 nontreated patients with intracerebral hemorrhage. Patients were treated or received standard medical management. All received EKG and cardiac enzyme testing. Elevated troponin occurred in 20% treated vs 3% nontreated (p = 0.02). Myocardial infarction occurred in 10% vs 1% (p = 0.01). We found a significant increase in myocardial injury in rFVIIa treated patients.

Original language	English (US)
Pages (from-to)	1053-1055
Number of pages	3
Journal	Neurology
Volume	67
Issue number	6
DOIs	https://doi.org/10.1212/01.wnl.0000239154.51331.c4
State	Published - Sep 2006
Externally published	Yes

ASJC Scopus subject areas

Clinical Neurology

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10.1212/01.wnl.0000239154.51331.c4

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title = "Myocardial injury in patients with intracerebral hemorrhage treated with recombinant factor VIIa",

abstract = "We report myocardial injury in 20 recombinant factor VIIa (rFVIIa) treated and 110 nontreated patients with intracerebral hemorrhage. Patients were treated or received standard medical management. All received EKG and cardiac enzyme testing. Elevated troponin occurred in 20\% treated vs 3\% nontreated (p = 0.02). Myocardial infarction occurred in 10\% vs 1\% (p = 0.01). We found a significant increase in myocardial injury in rFVIIa treated patients.",

author = "Sugg, \{R. M.\} and Gonzales, \{N. R.\} and Matherne, \{D. E.\} and M. Ribo and Shaltoni, \{H. M.\} and S. Baraniuk and Noser, \{E. A.\} and Grotta, \{J. C.\}",

note = "Funding Information: R.M.S., M.R., and N.R.G. were supported by NIH training grant \#T32NSO7412 to the University of Texas Houston Medical School Stroke Program. ",

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doi = "10.1212/01.wnl.0000239154.51331.c4",

language = "English (US)",

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T1 - Myocardial injury in patients with intracerebral hemorrhage treated with recombinant factor VIIa

AU - Sugg, R. M.

AU - Gonzales, N. R.

AU - Matherne, D. E.

AU - Ribo, M.

AU - Shaltoni, H. M.

AU - Baraniuk, S.

AU - Noser, E. A.

AU - Grotta, J. C.

N1 - Funding Information: R.M.S., M.R., and N.R.G. were supported by NIH training grant #T32NSO7412 to the University of Texas Houston Medical School Stroke Program.

PY - 2006/9

Y1 - 2006/9

N2 - We report myocardial injury in 20 recombinant factor VIIa (rFVIIa) treated and 110 nontreated patients with intracerebral hemorrhage. Patients were treated or received standard medical management. All received EKG and cardiac enzyme testing. Elevated troponin occurred in 20% treated vs 3% nontreated (p = 0.02). Myocardial infarction occurred in 10% vs 1% (p = 0.01). We found a significant increase in myocardial injury in rFVIIa treated patients.

AB - We report myocardial injury in 20 recombinant factor VIIa (rFVIIa) treated and 110 nontreated patients with intracerebral hemorrhage. Patients were treated or received standard medical management. All received EKG and cardiac enzyme testing. Elevated troponin occurred in 20% treated vs 3% nontreated (p = 0.02). Myocardial infarction occurred in 10% vs 1% (p = 0.01). We found a significant increase in myocardial injury in rFVIIa treated patients.

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Myocardial injury in patients with intracerebral hemorrhage treated with recombinant factor VIIa

Abstract

ASJC Scopus subject areas

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