Antibody levels to hantavirus in inhabitants of western Santa Catarina State, Brazil

William Marciel de Souza, Alex Martins Machado, Geonildo Rodrigo Disner, Everton Boff, Aline Rafaela da Silva Rodrigues Machado, Michelly de Padua, Luiz Tadeu Moraes Figueiredo, Gustavo Borba de Miranda

Research output: Contribution to journalArticlepeer-review

7 Scopus citations


Hantavirus cardiopulmonary syndrome (HCPS) is an infectious disease caused by hantaviruses of the family Bunyaviridae, and is transmitted by aerosols of excreta of infected rodents. The aim of the present study was to determine antibody levels to hantavirus in the population that lives at frontier of Brazil and Argentina. Participated of the study 405 individuals living in the municipalities of Bandeirante, Santa Helena, Princesa and Tunapolis, state of Santa Catarina, Brazil. IgG antibodies to hantavirus were analyzed in sera by an ELISA that uses a recombinant N protein of Araraquara hantavirus as antigen. The results were also confirmed by immunofluorescent test. Eight individuals showed antibodies to hantavirus (1.97% positivity), with serum titers ranging from 100 to 800. Six seropositives were males, older than 30 years and farmers. Our results reinforce previous data on hantavirus circulation and human infections in the southern border of Brazil with Argentina.

Original languageEnglish (US)
Pages (from-to)193-196
Number of pages4
JournalRevista do Instituto de Medicina Tropical de Sao Paulo
Issue number4
StatePublished - Jul 2012
Externally publishedYes


  • Argentina
  • Brazil
  • Epidemiology
  • Hantavirus
  • Santa Catarina

ASJC Scopus subject areas

  • Infectious Diseases


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