Nanoscale engineering of a cellular interface with semiconductor nanoparticle films for photoelectric stimulation of neurons

Todd C. Pappas, W. M Shan Wickramanyake, Edward Jan, Massoud Motamedi, Malcolm Brodwick, Nicholas A. Kotov

Research output: Contribution to journalArticle

98 Citations (Scopus)

Abstract

The remarkable optical and electrical properties of nanostructured materials are considered now as a source for a variety of biomaterials, biosensing, and cell interface applications. In this study, we report the first example of hybrid bionanodevice where absorption of light by thin films of quantum confined semiconductor nanoparticles of HgTe produced by the layer-by-layer assembly stimulate adherent neural cells via a sequence of photochemical and charge-transfer reactions. We also demonstrate an example of nanoscale engineering of the material driven by biological functionalities.

Original languageEnglish (US)
Pages (from-to)513-519
Number of pages7
JournalNano Letters
Volume7
Issue number2
DOIs
StatePublished - Feb 2007

Fingerprint

Biocompatible Materials
neurons
stimulation
Nanostructured materials
Biomaterials
Neurons
Charge transfer
Electric properties
Optical properties
engineering
Semiconductor materials
Nanoparticles
Thin films
nanoparticles
cells
assembly
electrical properties
charge transfer
optical properties
thin films

ASJC Scopus subject areas

  • Materials Science(all)
  • Electronic, Optical and Magnetic Materials
  • Chemistry (miscellaneous)

Cite this

Nanoscale engineering of a cellular interface with semiconductor nanoparticle films for photoelectric stimulation of neurons. / Pappas, Todd C.; Wickramanyake, W. M Shan; Jan, Edward; Motamedi, Massoud; Brodwick, Malcolm; Kotov, Nicholas A.

In: Nano Letters, Vol. 7, No. 2, 02.2007, p. 513-519.

Research output: Contribution to journalArticle

Pappas, Todd C. ; Wickramanyake, W. M Shan ; Jan, Edward ; Motamedi, Massoud ; Brodwick, Malcolm ; Kotov, Nicholas A. / Nanoscale engineering of a cellular interface with semiconductor nanoparticle films for photoelectric stimulation of neurons. In: Nano Letters. 2007 ; Vol. 7, No. 2. pp. 513-519.
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