Nanoscale engineering of a cellular interface with semiconductor nanoparticle films for photoelectric stimulation of neurons

Todd C. Pappas, W. M.Shan Wickramanyake, Edward Jan, Massoud Motamedi, Malcolm Brodwick, Nicholas A. Kotov

    Research output: Contribution to journalArticlepeer-review

    124 Scopus citations

    Abstract

    The remarkable optical and electrical properties of nanostructured materials are considered now as a source for a variety of biomaterials, biosensing, and cell interface applications. In this study, we report the first example of hybrid bionanodevice where absorption of light by thin films of quantum confined semiconductor nanoparticles of HgTe produced by the layer-by-layer assembly stimulate adherent neural cells via a sequence of photochemical and charge-transfer reactions. We also demonstrate an example of nanoscale engineering of the material driven by biological functionalities.

    Original languageEnglish (US)
    Pages (from-to)513-519
    Number of pages7
    JournalNano Letters
    Volume7
    Issue number2
    DOIs
    StatePublished - Feb 2007

    ASJC Scopus subject areas

    • Bioengineering
    • Chemistry(all)
    • Materials Science(all)
    • Condensed Matter Physics
    • Mechanical Engineering

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