Natural and nosocomial infection in a patient with West Nile encephalitis and extrapyramidal movement disorders.

Tom Solomon, Ann F. Fisher, David W C Beasley, Pitchaiah Mandava, Bruno P. Granwehr, Hans Langsjoen, Amelia P. Travassos Da Rosa, Alan D T Barrett, Robert B. Tesh

Research output: Contribution to journalArticle

36 Citations (Scopus)

Abstract

Since its first recognition in North America in 1999, West Nile virus (WNV) has spread rapidly across the continent, but in many communities, rapid diagnostic tests for detection of WNV infection are not fully available. We describe a patient with extrapyramidal movement disorders and changes in the basal ganglia noted on magnetic resonance images that are characteristic of other flavivirus encephalitides and may help in the recognition of patients with West Nile encephalitis. Detailed molecular analysis suggested that, although our patient received a blood transfusion infected with WNV, the virus that caused his initial infection and encephalitis was probably acquired naturally from a mosquito.

Original languageEnglish (US)
JournalClinical infectious diseases : an official publication of the Infectious Diseases Society of America
Volume36
Issue number11
StatePublished - 2003

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Basal Ganglia Diseases
West Nile virus
Movement Disorders
Encephalitis
Cross Infection
Flavivirus
Virus Diseases
North America
Basal Ganglia
Culicidae
Routine Diagnostic Tests
Blood Transfusion
Magnetic Resonance Spectroscopy
Viruses

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Natural and nosocomial infection in a patient with West Nile encephalitis and extrapyramidal movement disorders. / Solomon, Tom; Fisher, Ann F.; Beasley, David W C; Mandava, Pitchaiah; Granwehr, Bruno P.; Langsjoen, Hans; Travassos Da Rosa, Amelia P.; Barrett, Alan D T; Tesh, Robert B.

In: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, Vol. 36, No. 11, 2003.

Research output: Contribution to journalArticle

Solomon, Tom ; Fisher, Ann F. ; Beasley, David W C ; Mandava, Pitchaiah ; Granwehr, Bruno P. ; Langsjoen, Hans ; Travassos Da Rosa, Amelia P. ; Barrett, Alan D T ; Tesh, Robert B. / Natural and nosocomial infection in a patient with West Nile encephalitis and extrapyramidal movement disorders. In: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. 2003 ; Vol. 36, No. 11.
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