Natural rodent host associations of Guanarito and Pirital viruses (family Arenaviridae) in central Venezuela

Charles F. Fulhorst, Michael D. Bowen, Rosa Alba Salas, Gloria Duno, Antonio Utrera, Thomas G. Ksiazek, Nuris M.C. De Manzione, Edith De Miller, Clovis Vasquez, Clarence J. Peters, Robert B. Tesh

Research output: Contribution to journalArticle

57 Scopus citations

Abstract

The objective of this study was to elucidate the natural rodent host relationships of Guanarito and Pirital viruses (family Arenaviridae) in the plains of central Venezuela. Ninety-two arenavirus isolates from 607 animals, representing 10 different rodent species, were characterized to the level of serotype. The 92 isolates comprised 19 Guanarito virus strains and 73 Pirital virus strains. The 19 Guanarito virus isolates were from Zygodontornys brevicauda; 72 (98.6%) of the 73 Pirital virus isolates were from Sigmodon alstoni. These results indicate that the natural rodent associations of these 2 sympatric arenaviruses are highly specific and that Z. brevicauda and S. alstoni are the principal rodent hosts of Guanarito and Pirital viruses, respectively.

Original languageEnglish (US)
Pages (from-to)325-330
Number of pages6
JournalAmerican Journal of Tropical Medicine and Hygiene
Volume61
Issue number2
DOIs
StatePublished - Aug 1999
Externally publishedYes

ASJC Scopus subject areas

  • Parasitology
  • Virology
  • Infectious Diseases

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    Fulhorst, C. F., Bowen, M. D., Salas, R. A., Duno, G., Utrera, A., Ksiazek, T. G., De Manzione, N. M. C., De Miller, E., Vasquez, C., Peters, C. J., & Tesh, R. B. (1999). Natural rodent host associations of Guanarito and Pirital viruses (family Arenaviridae) in central Venezuela. American Journal of Tropical Medicine and Hygiene, 61(2), 325-330. https://doi.org/10.4269/ajtmh.1999.61.325