Naturally occurring mutations alter the stability of polycystin-1 polycystic kidney disease (PKD) domains

Medicine & Life Sciences

• polycystic kidney disease 1 protein 100%
• Polycystic Kidney Diseases 80%
• Missense Mutation 38%
• Mutation 34%
• Autosomal Dominant Polycystic Kidney 32%
• Thermodynamics 15%
• Cilia 14%
• Renal Insufficiency 10%
• Extracellular Matrix 10%
• Membrane Proteins 10%
• Amino Acids 8%
• Phenotype 7%

Chemical Compounds

• Mutation 52%
• Thermodynamics 5%
• Protein 3%
• Acid 3%